FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000347987> ?p ?o ?g. }

• W2000347987 endingPage "599" @default.
• W2000347987 startingPage "594" @default.
• W2000347987 abstract "Recent research indicates that cumulative exposure to lead may be more toxic than previously thought. This study was undertaken to examine the relation of low-level lead exposure to electrocardiographic (ECG) conduction disturbances among 775 men who participated in the Normative Aging Study (average age 68 years; range 48 to 93). We used K-x-ray fluorescence to measure lead levels in the tibia and patella, and graphite furnace atomic absorption spectroscopy to measure blood lead levels. The mean (SD) values for blood lead, tibia lead, and patella lead were 5.8 (3.4) microg/dl, 22.2 (13.4) microg/g, and 30.8 (19.2) microg/g, respectively. Bone lead levels were found to be positively associated with heart rate-corrected QT and QRS intervals, especially in younger men. Specifically, in men <65 years of age, a 10 microg/g increase in tibia lead was associated with an increase in the QT interval of 5.03 ms (95% confidence interval [CI], 0.83 to 9.22) and with an increase in the QRS interval of 4.83 ms (95% CI, 1.83 to 7.83) in multivariate regression models. In addition, an elevated bone lead level was found to be positively associated with an increased risk of intraventricular block in men <65 years of age and with an increased risk of atrioventricular (AV) block in men > or = 65 years of age. After adjustment for age and for serum high-density lipoprotein (HDL) level, a 10 microg/g increase in tibia lead was associated with an odds ratio (OR) of 2.23 (95% CI, 1.28 to 3.90) for intraventricular block in men <65 years of age and with an OR of 1.22 (95% CI, 1.02 to 1.47) for AV block in men > or = 65 years of age. Blood lead level was not associated with any of the ECG outcomes examined. The results suggest that cumulative exposure to lead, even at low levels, may depress cardiac conduction." @default.
• W2000347987 created "2016-06-24" @default.
• W2000347987 creator A5033355210 @default.
• W2000347987 creator A5046557560 @default.
• W2000347987 creator A5055314934 @default.
• W2000347987 creator A5073763243 @default.
• W2000347987 creator A5078987114 @default.
• W2000347987 creator A5091155976 @default.
• W2000347987 date "1998-09-01" @default.
• W2000347987 modified "2023-10-12" @default.
• W2000347987 title "Electrocardiographic conduction disturbances in association with low-level lead exposure (the Normative Aging Study)" @default.
• W2000347987 cites W1551425506 @default.
• W2000347987 cites W1980207364 @default.
• W2000347987 cites W1992436361 @default.
• W2000347987 cites W2009048447 @default.
• W2000347987 cites W2014276861 @default.
• W2000347987 cites W2021098812 @default.
• W2000347987 cites W2022592612 @default.
• W2000347987 cites W2030447524 @default.
• W2000347987 cites W2030872036 @default.
• W2000347987 cites W2048506613 @default.
• W2000347987 cites W2049798493 @default.
• W2000347987 cites W2054636618 @default.
• W2000347987 cites W2089592279 @default.
• W2000347987 cites W2094126916 @default.
• W2000347987 cites W2108377252 @default.
• W2000347987 cites W2127467308 @default.
• W2000347987 cites W2168605218 @default.
• W2000347987 cites W4320300838 @default.
• W2000347987 cites W99886105 @default.
• W2000347987 doi "https://doi.org/10.1016/s0002-9149(98)00402-0" @default.
• W2000347987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9732886" @default.
• W2000347987 hasPublicationYear "1998" @default.
• W2000347987 type Work @default.
• W2000347987 sameAs 2000347987 @default.
• W2000347987 citedByCount "71" @default.
• W2000347987 countsByYear W20003479872012 @default.
• W2000347987 countsByYear W20003479872013 @default.
• W2000347987 countsByYear W20003479872014 @default.
• W2000347987 countsByYear W20003479872015 @default.
• W2000347987 countsByYear W20003479872016 @default.
• W2000347987 countsByYear W20003479872017 @default.
• W2000347987 countsByYear W20003479872018 @default.
• W2000347987 countsByYear W20003479872021 @default.
• W2000347987 countsByYear W20003479872022 @default.
• W2000347987 crossrefType "journal-article" @default.
• W2000347987 hasAuthorship W2000347987A5033355210 @default.
• W2000347987 hasAuthorship W2000347987A5046557560 @default.
• W2000347987 hasAuthorship W2000347987A5055314934 @default.
• W2000347987 hasAuthorship W2000347987A5073763243 @default.
• W2000347987 hasAuthorship W2000347987A5078987114 @default.
• W2000347987 hasAuthorship W2000347987A5091155976 @default.
• W2000347987 hasConcept C111773187 @default.
• W2000347987 hasConcept C114793014 @default.
• W2000347987 hasConcept C118441451 @default.
• W2000347987 hasConcept C126322002 @default.
• W2000347987 hasConcept C127313418 @default.
• W2000347987 hasConcept C141071460 @default.
• W2000347987 hasConcept C164705383 @default.
• W2000347987 hasConcept C178697064 @default.
• W2000347987 hasConcept C2777093003 @default.
• W2000347987 hasConcept C2777236700 @default.
• W2000347987 hasConcept C2777953023 @default.
• W2000347987 hasConcept C2779904517 @default.
• W2000347987 hasConcept C3020026551 @default.
• W2000347987 hasConcept C44249647 @default.
• W2000347987 hasConcept C71924100 @default.
• W2000347987 hasConcept C84393581 @default.
• W2000347987 hasConceptScore W2000347987C111773187 @default.
• W2000347987 hasConceptScore W2000347987C114793014 @default.
• W2000347987 hasConceptScore W2000347987C118441451 @default.
• W2000347987 hasConceptScore W2000347987C126322002 @default.
• W2000347987 hasConceptScore W2000347987C127313418 @default.
• W2000347987 hasConceptScore W2000347987C141071460 @default.
• W2000347987 hasConceptScore W2000347987C164705383 @default.
• W2000347987 hasConceptScore W2000347987C178697064 @default.
• W2000347987 hasConceptScore W2000347987C2777093003 @default.
• W2000347987 hasConceptScore W2000347987C2777236700 @default.
• W2000347987 hasConceptScore W2000347987C2777953023 @default.
• W2000347987 hasConceptScore W2000347987C2779904517 @default.
• W2000347987 hasConceptScore W2000347987C3020026551 @default.
• W2000347987 hasConceptScore W2000347987C44249647 @default.
• W2000347987 hasConceptScore W2000347987C71924100 @default.
• W2000347987 hasConceptScore W2000347987C84393581 @default.
• W2000347987 hasIssue "5" @default.
• W2000347987 hasLocation W20003479871 @default.
• W2000347987 hasLocation W20003479872 @default.
• W2000347987 hasOpenAccess W2000347987 @default.
• W2000347987 hasPrimaryLocation W20003479871 @default.
• W2000347987 hasRelatedWork W1967172296 @default.
• W2000347987 hasRelatedWork W2156861234 @default.
• W2000347987 hasRelatedWork W2322068018 @default.
• W2000347987 hasRelatedWork W2328869522 @default.
• W2000347987 hasRelatedWork W2385758789 @default.
• W2000347987 hasRelatedWork W2609306612 @default.
• W2000347987 hasRelatedWork W2994442156 @default.
• W2000347987 hasRelatedWork W4211093051 @default.
• W2000347987 hasRelatedWork W4235293565 @default.

• next