FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000353797> ?p ?o ?g. }

• W2000353797 endingPage "864" @default.
• W2000353797 startingPage "857" @default.
• W2000353797 abstract "Although insulin resistance and elevated plasma homocysteine are associated with hypertension in adults, the role of these conditions in the initial phase of hypertension is largely unknown. We examined whether insulin resistance and disturbed homocysteine metabolism are present in young adults at the early stages of essential hypertension.We measured physical characteristics, plasma levels of insulin, lipids, total homocysteine, and vitamins in 164 patients with essential juvenile hypertension (median age, 19 years; 92% males) and in 173 controls (median age, 18 years; 66% males). Furthermore, we analyzed the prevalence of six polymorphisms in four genes of the methionine cycle.Patients with hypertension and controls differed significantly (P <.05) in body mass index, levels of insulin, high-density lipoprotein-cholesterol, fasting and post-load plasma homocysteine, and folates. Systolic blood pressure was correlated with homocysteine levels and inversely correlated with plasma folates. Logistic regression showed that fasting homocysteine, vitamin B(12), and low-density lipoprotein-cholesterol were associated with a significantly increased risk of juvenile hypertension. In contrast, the birth length, polymorphism c.2756 A-->G in the MTR gene and plasma folate were associated with a significantly decreased risk of juvenile hypertension.Our study showed that essential hypertension in adolescents is associated with lower folate and higher homocysteine levels, and with signs of insulin resistance. These data suggest that hypertension in young individuals may be a part of early manifestation of insulin resistance syndrome, and that disturbed folate and homocysteine metabolism may play a role in the early stages of hypertension." @default.
• W2000353797 created "2016-06-24" @default.
• W2000353797 creator A5021943133 @default.
• W2000353797 creator A5025210614 @default.
• W2000353797 creator A5032513017 @default.
• W2000353797 creator A5037252053 @default.
• W2000353797 creator A5039848607 @default.
• W2000353797 creator A5043315510 @default.
• W2000353797 creator A5052640193 @default.
• W2000353797 creator A5071980210 @default.
• W2000353797 creator A5084682118 @default.
• W2000353797 date "2002-10-01" @default.
• W2000353797 modified "2023-10-16" @default.
• W2000353797 title "Essential hypertension in adolescents: association with insulin resistance and with metabolism of homocysteine and vitamins" @default.
• W2000353797 cites W1816872835 @default.
• W2000353797 cites W1902500413 @default.
• W2000353797 cites W1965119761 @default.
• W2000353797 cites W1966292733 @default.
• W2000353797 cites W1975357252 @default.
• W2000353797 cites W1977357923 @default.
• W2000353797 cites W1987171082 @default.
• W2000353797 cites W1988675954 @default.
• W2000353797 cites W1995781460 @default.
• W2000353797 cites W2040429583 @default.
• W2000353797 cites W2059993417 @default.
• W2000353797 cites W2065588399 @default.
• W2000353797 cites W2067316789 @default.
• W2000353797 cites W2070690822 @default.
• W2000353797 cites W2083659967 @default.
• W2000353797 cites W2088080019 @default.
• W2000353797 cites W2091727242 @default.
• W2000353797 cites W2099005196 @default.
• W2000353797 cites W2108484297 @default.
• W2000353797 cites W2109788909 @default.
• W2000353797 cites W2111521328 @default.
• W2000353797 cites W2112750586 @default.
• W2000353797 cites W2119831577 @default.
• W2000353797 cites W2131999937 @default.
• W2000353797 cites W2132028324 @default.
• W2000353797 cites W2141704734 @default.
• W2000353797 cites W2151172803 @default.
• W2000353797 cites W2160618836 @default.
• W2000353797 cites W2166298177 @default.
• W2000353797 cites W2329739961 @default.
• W2000353797 cites W2502796181 @default.
• W2000353797 cites W46688545 @default.
• W2000353797 doi "https://doi.org/10.1016/s0895-7061(02)02984-9" @default.
• W2000353797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12372672" @default.
• W2000353797 hasPublicationYear "2002" @default.
• W2000353797 type Work @default.
• W2000353797 sameAs 2000353797 @default.
• W2000353797 citedByCount "85" @default.
• W2000353797 countsByYear W20003537972012 @default.
• W2000353797 countsByYear W20003537972013 @default.
• W2000353797 countsByYear W20003537972014 @default.
• W2000353797 countsByYear W20003537972015 @default.
• W2000353797 countsByYear W20003537972016 @default.
• W2000353797 countsByYear W20003537972017 @default.
• W2000353797 countsByYear W20003537972018 @default.
• W2000353797 countsByYear W20003537972019 @default.
• W2000353797 countsByYear W20003537972020 @default.
• W2000353797 countsByYear W20003537972021 @default.
• W2000353797 countsByYear W20003537972022 @default.
• W2000353797 countsByYear W20003537972023 @default.
• W2000353797 crossrefType "journal-article" @default.
• W2000353797 hasAuthorship W2000353797A5021943133 @default.
• W2000353797 hasAuthorship W2000353797A5025210614 @default.
• W2000353797 hasAuthorship W2000353797A5032513017 @default.
• W2000353797 hasAuthorship W2000353797A5037252053 @default.
• W2000353797 hasAuthorship W2000353797A5039848607 @default.
• W2000353797 hasAuthorship W2000353797A5043315510 @default.
• W2000353797 hasAuthorship W2000353797A5052640193 @default.
• W2000353797 hasAuthorship W2000353797A5071980210 @default.
• W2000353797 hasAuthorship W2000353797A5084682118 @default.
• W2000353797 hasBestOaLocation W20003537971 @default.
• W2000353797 hasConcept C104317684 @default.
• W2000353797 hasConcept C126322002 @default.
• W2000353797 hasConcept C134018914 @default.
• W2000353797 hasConcept C135763542 @default.
• W2000353797 hasConcept C2777090595 @default.
• W2000353797 hasConcept C2777097880 @default.
• W2000353797 hasConcept C2777391703 @default.
• W2000353797 hasConcept C2779306644 @default.
• W2000353797 hasConcept C3020471959 @default.
• W2000353797 hasConcept C43563269 @default.
• W2000353797 hasConcept C55493867 @default.
• W2000353797 hasConcept C71924100 @default.
• W2000353797 hasConcept C84393581 @default.
• W2000353797 hasConcept C86803240 @default.
• W2000353797 hasConceptScore W2000353797C104317684 @default.
• W2000353797 hasConceptScore W2000353797C126322002 @default.
• W2000353797 hasConceptScore W2000353797C134018914 @default.
• W2000353797 hasConceptScore W2000353797C135763542 @default.
• W2000353797 hasConceptScore W2000353797C2777090595 @default.
• W2000353797 hasConceptScore W2000353797C2777097880 @default.
• W2000353797 hasConceptScore W2000353797C2777391703 @default.
• W2000353797 hasConceptScore W2000353797C2779306644 @default.
• W2000353797 hasConceptScore W2000353797C3020471959 @default.

• next