FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000356509> ?p ?o ?g. }

• W2000356509 endingPage "i88" @default.
• W2000356509 startingPage "i83" @default.
• W2000356509 abstract "<h3>Introduction</h3> Small renal masses (SRMs; ≤4 cm) account for two-thirds of new diagnoses of kidney cancer, the majority of which are incidental findings. The natural history of the SRM seems largely indolent. There is an increasing concern regarding surgical overtreatment and the associated health burden in terms of morbidity and economy. Observational data support the safety and efficacy of percutaneous cryoablation but there is an unmet need for high-quality evidence on non-surgical management options and a head-to-head comparison with standard of care is lacking. Historical interventional trial recruitment difficulties demand novel study conduct approaches. We aim to assess if a novel trial design, the cohort embedded randomised controlled trial (RCT), will enable carrying out such a comparison. <h3>Methods and analysis</h3> Single-centre prospective cohort study of adults diagnosed with SRM (n=200) with an open label embedded interventional RCT comparing nephron sparing interventions. Cohort participants will be managed at patient and clinicians’ discretion and agree with longitudinal clinical data and biological sample collection, with invitation for trial interventions and participation in comparator control groups. Cohort participants with biopsy-proven renal cell carcinoma eligible for both percutaneous cryoablation and partial nephrectomy will be randomly selected (1:1) and invited to consider percutaneous cryoablation (n=25). The comparator group will be robotic partial nephrectomy (n=25). The primary outcome of this feasibility study is participant recruitment. Qualitative research techniques will assess barriers and recruitment improvement opportunities. Secondary outcomes are participant trial retention, health-related quality of life, treatment complications, blood transfusion rate, intensive care unit admission and renal replacement requirement rates, length of hospital stay, time to return to pre-treatment activities, number of work days lost, and health technologies costs. <h3>Ethics and dissemination</h3> Ethical approval has been granted (UK HRA REC 19/EM/0004). Study outputs will be presented and published. <h3>Trial registration</h3> ISRCTN18156881; Pre-results." @default.
• W2000356509 created "2016-06-24" @default.
• W2000356509 creator A5016018286 @default.
• W2000356509 creator A5018165332 @default.
• W2000356509 creator A5019518752 @default.
• W2000356509 creator A5036812227 @default.
• W2000356509 creator A5062756331 @default.
• W2000356509 creator A5074273891 @default.
• W2000356509 creator A5079519343 @default.
• W2000356509 date "2010-02-01" @default.
• W2000356509 modified "2023-10-01" @default.
• W2000356509 title "Quality assurance and quality improvement using supportive supervision in a large-scale STI intervention with sex workers, men who have sex with men/transgenders and injecting-drug users in India" @default.
• W2000356509 cites W1508378410 @default.
• W2000356509 cites W1973954452 @default.
• W2000356509 cites W1974626697 @default.
• W2000356509 cites W1985403559 @default.
• W2000356509 cites W1985843074 @default.
• W2000356509 cites W1985881835 @default.
• W2000356509 cites W1996568972 @default.
• W2000356509 cites W2034492413 @default.
• W2000356509 cites W2041131848 @default.
• W2000356509 cites W2046987711 @default.
• W2000356509 cites W2083904840 @default.
• W2000356509 cites W2090472613 @default.
• W2000356509 cites W2103937284 @default.
• W2000356509 cites W2111819007 @default.
• W2000356509 cites W2114967869 @default.
• W2000356509 cites W2117806567 @default.
• W2000356509 cites W2133783545 @default.
• W2000356509 cites W2135536889 @default.
• W2000356509 cites W2139797352 @default.
• W2000356509 cites W2184198306 @default.
• W2000356509 cites W2234518824 @default.
• W2000356509 cites W2287459399 @default.
• W2000356509 cites W2325778137 @default.
• W2000356509 cites W2435222815 @default.
• W2000356509 cites W2488437366 @default.
• W2000356509 cites W2606887753 @default.
• W2000356509 cites W3022274619 @default.
• W2000356509 cites W43902372 @default.
• W2000356509 cites W72215699 @default.
• W2000356509 doi "https://doi.org/10.1136/sti.2009.038364" @default.
• W2000356509 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3252614" @default.
• W2000356509 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20167739" @default.
• W2000356509 hasPublicationYear "2010" @default.
• W2000356509 type Work @default.
• W2000356509 sameAs 2000356509 @default.
• W2000356509 citedByCount "28" @default.
• W2000356509 countsByYear W20003565092012 @default.
• W2000356509 countsByYear W20003565092013 @default.
• W2000356509 countsByYear W20003565092014 @default.
• W2000356509 countsByYear W20003565092015 @default.
• W2000356509 countsByYear W20003565092016 @default.
• W2000356509 countsByYear W20003565092018 @default.
• W2000356509 countsByYear W20003565092019 @default.
• W2000356509 countsByYear W20003565092021 @default.
• W2000356509 countsByYear W20003565092022 @default.
• W2000356509 countsByYear W20003565092023 @default.
• W2000356509 crossrefType "journal-article" @default.
• W2000356509 hasAuthorship W2000356509A5016018286 @default.
• W2000356509 hasAuthorship W2000356509A5018165332 @default.
• W2000356509 hasAuthorship W2000356509A5019518752 @default.
• W2000356509 hasAuthorship W2000356509A5036812227 @default.
• W2000356509 hasAuthorship W2000356509A5062756331 @default.
• W2000356509 hasAuthorship W2000356509A5074273891 @default.
• W2000356509 hasAuthorship W2000356509A5079519343 @default.
• W2000356509 hasBestOaLocation W20003565091 @default.
• W2000356509 hasConcept C126322002 @default.
• W2000356509 hasConcept C141071460 @default.
• W2000356509 hasConcept C159110408 @default.
• W2000356509 hasConcept C168563851 @default.
• W2000356509 hasConcept C1862650 @default.
• W2000356509 hasConcept C27415008 @default.
• W2000356509 hasConcept C2777628079 @default.
• W2000356509 hasConcept C2778902805 @default.
• W2000356509 hasConcept C535046627 @default.
• W2000356509 hasConcept C71924100 @default.
• W2000356509 hasConcept C72563966 @default.
• W2000356509 hasConceptScore W2000356509C126322002 @default.
• W2000356509 hasConceptScore W2000356509C141071460 @default.
• W2000356509 hasConceptScore W2000356509C159110408 @default.
• W2000356509 hasConceptScore W2000356509C168563851 @default.
• W2000356509 hasConceptScore W2000356509C1862650 @default.
• W2000356509 hasConceptScore W2000356509C27415008 @default.
• W2000356509 hasConceptScore W2000356509C2777628079 @default.
• W2000356509 hasConceptScore W2000356509C2778902805 @default.
• W2000356509 hasConceptScore W2000356509C535046627 @default.
• W2000356509 hasConceptScore W2000356509C71924100 @default.
• W2000356509 hasConceptScore W2000356509C72563966 @default.
• W2000356509 hasIssue "Suppl 1" @default.
• W2000356509 hasLocation W20003565091 @default.
• W2000356509 hasLocation W20003565092 @default.
• W2000356509 hasLocation W20003565093 @default.
• W2000356509 hasLocation W20003565094 @default.
• W2000356509 hasLocation W20003565095 @default.
• W2000356509 hasLocation W20003565096 @default.
• W2000356509 hasOpenAccess W2000356509 @default.
• W2000356509 hasPrimaryLocation W20003565091 @default.

• next