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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000359207> ?p ?o ?g. }

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• W2000359207 abstract "The design of a series of peptidomimetic inhibitors of the hepatitis C virus NS3 protease is described. These inhibitors feature an indoline-2-carboxamide as a novel heterocyclic replacement for the P3 amino acid residue and N-terminal capping group of tripeptide based inhibitors. The crystal structure of the ternary NS3/NS4A/inhibitor complex for the most active molecule in this series highlights its suitability as an N-terminal capping group of a dipeptide inhibitor of the NS3 protease." @default.
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• W2000359207 date "2004-11-13" @default.
• W2000359207 modified "2023-10-17" @default.
• W2000359207 title "The Design and Enzyme-Bound Crystal Structure of Indoline Based Peptidomimetic Inhibitors of Hepatitis C Virus NS3 Protease" @default.
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• W2000359207 doi "https://doi.org/10.1021/jm049435d" @default.
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