Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000362479> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2000362479 endingPage "493" @default.
- W2000362479 startingPage "486" @default.
- W2000362479 abstract "Wiskott-Aldrich syndrome is characterized by numerous humoral and cellular immune abnormalities including anergy, defective antibody production, and increased immunoglobulin synthesis. To define better the mechanisms of defective cellular immunity in this disorder, lymphoproliferative responses, lymphokine production, and the chemotactic responsiveness of mononuclear leukocytes (MNL) from patients with Wiskott-Aldrich syndrome were quantitated. Peripheral blood lymphocytes from these patients produced normal amounts of a lymphocyte-derived chemotactic factor (LDCF); however, their lymphoproliferative responses were frequently depressed, particularly to antigenic stimuli. In the absence of exogenous antigens or mitogens, lymphocytes from patients with Wiskott-Aldrich syndrome produced significantly more LDCF than unstimulated normal lymphocytes. In fact, this unstimulated LDCF production frequently approached the level produced by normal cells only after antigen or mitogen stimulation." @default.
- W2000362479 created "2016-06-24" @default.
- W2000362479 creator A5006734371 @default.
- W2000362479 creator A5007865413 @default.
- W2000362479 creator A5020405246 @default.
- W2000362479 date "1974-08-01" @default.
- W2000362479 modified "2023-09-23" @default.
- W2000362479 title "Abnormalities of Chemotactic Lymphokine Synthesis and Mononuclear Leukocyte Chemotaxis in Wiskott-Aldrich Syndrome" @default.
- W2000362479 cites W1625160398 @default.
- W2000362479 cites W1881108563 @default.
- W2000362479 cites W1894152991 @default.
- W2000362479 cites W1946681269 @default.
- W2000362479 cites W2013858124 @default.
- W2000362479 cites W2015907128 @default.
- W2000362479 cites W2018394231 @default.
- W2000362479 cites W2029053256 @default.
- W2000362479 cites W2047721998 @default.
- W2000362479 cites W2057817068 @default.
- W2000362479 cites W2070993621 @default.
- W2000362479 cites W2075338554 @default.
- W2000362479 cites W2082013662 @default.
- W2000362479 cites W2117228071 @default.
- W2000362479 cites W2329211716 @default.
- W2000362479 cites W2409121355 @default.
- W2000362479 cites W4297040010 @default.
- W2000362479 cites W81571208 @default.
- W2000362479 doi "https://doi.org/10.1172/jci107784" @default.
- W2000362479 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/301576" @default.
- W2000362479 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4136226" @default.
- W2000362479 hasPublicationYear "1974" @default.
- W2000362479 type Work @default.
- W2000362479 sameAs 2000362479 @default.
- W2000362479 citedByCount "93" @default.
- W2000362479 countsByYear W20003624792014 @default.
- W2000362479 countsByYear W20003624792020 @default.
- W2000362479 countsByYear W20003624792022 @default.
- W2000362479 crossrefType "journal-article" @default.
- W2000362479 hasAuthorship W2000362479A5006734371 @default.
- W2000362479 hasAuthorship W2000362479A5007865413 @default.
- W2000362479 hasAuthorship W2000362479A5020405246 @default.
- W2000362479 hasBestOaLocation W20003624791 @default.
- W2000362479 hasConcept C104317684 @default.
- W2000362479 hasConcept C137061746 @default.
- W2000362479 hasConcept C147483822 @default.
- W2000362479 hasConcept C170493617 @default.
- W2000362479 hasConcept C202751555 @default.
- W2000362479 hasConcept C203014093 @default.
- W2000362479 hasConcept C2776969849 @default.
- W2000362479 hasConcept C2777761686 @default.
- W2000362479 hasConcept C2778153459 @default.
- W2000362479 hasConcept C3017875465 @default.
- W2000362479 hasConcept C49382859 @default.
- W2000362479 hasConcept C54166955 @default.
- W2000362479 hasConcept C55493867 @default.
- W2000362479 hasConcept C86803240 @default.
- W2000362479 hasConcept C8891405 @default.
- W2000362479 hasConceptScore W2000362479C104317684 @default.
- W2000362479 hasConceptScore W2000362479C137061746 @default.
- W2000362479 hasConceptScore W2000362479C147483822 @default.
- W2000362479 hasConceptScore W2000362479C170493617 @default.
- W2000362479 hasConceptScore W2000362479C202751555 @default.
- W2000362479 hasConceptScore W2000362479C203014093 @default.
- W2000362479 hasConceptScore W2000362479C2776969849 @default.
- W2000362479 hasConceptScore W2000362479C2777761686 @default.
- W2000362479 hasConceptScore W2000362479C2778153459 @default.
- W2000362479 hasConceptScore W2000362479C3017875465 @default.
- W2000362479 hasConceptScore W2000362479C49382859 @default.
- W2000362479 hasConceptScore W2000362479C54166955 @default.
- W2000362479 hasConceptScore W2000362479C55493867 @default.
- W2000362479 hasConceptScore W2000362479C86803240 @default.
- W2000362479 hasConceptScore W2000362479C8891405 @default.
- W2000362479 hasIssue "2" @default.
- W2000362479 hasLocation W20003624791 @default.
- W2000362479 hasLocation W20003624792 @default.
- W2000362479 hasLocation W20003624793 @default.
- W2000362479 hasLocation W20003624794 @default.
- W2000362479 hasOpenAccess W2000362479 @default.
- W2000362479 hasPrimaryLocation W20003624791 @default.
- W2000362479 hasRelatedWork W1968317909 @default.
- W2000362479 hasRelatedWork W2000362479 @default.
- W2000362479 hasRelatedWork W2046675747 @default.
- W2000362479 hasRelatedWork W2070993621 @default.
- W2000362479 hasRelatedWork W2220102944 @default.
- W2000362479 hasRelatedWork W2402307906 @default.
- W2000362479 hasRelatedWork W2409441623 @default.
- W2000362479 hasRelatedWork W2409579824 @default.
- W2000362479 hasRelatedWork W2415361595 @default.
- W2000362479 hasRelatedWork W1988261318 @default.
- W2000362479 hasVolume "54" @default.
- W2000362479 isParatext "false" @default.
- W2000362479 isRetracted "false" @default.
- W2000362479 magId "2000362479" @default.
- W2000362479 workType "article" @default.