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- W2000367437 abstract "Histamine-containing neurons and histamine H1 receptors are distributed within the brain and peripheral tissues. The results of physiological and pharmacological studies have revealed that brain histamine and H1 receptors are involved in the regulation of feeding and obesity in rodents. The adipocytokine leptin regulates feeding and obesity, partially through brain histamine. Furthermore, recent studies have provided evidence that regulation of the diurnal rhythm of feeding through H1 receptors is a crucial factor in the development of obesity. Thus, the regulation of H1 receptors is important for the control of energy metabolism, feeding rhythms and obesity in rodents. Histamine-containing neurons and histamine H1 receptors are distributed within the brain and peripheral tissues. The results of physiological and pharmacological studies have revealed that brain histamine and H1 receptors are involved in the regulation of feeding and obesity in rodents. The adipocytokine leptin regulates feeding and obesity, partially through brain histamine. Furthermore, recent studies have provided evidence that regulation of the diurnal rhythm of feeding through H1 receptors is a crucial factor in the development of obesity. Thus, the regulation of H1 receptors is important for the control of energy metabolism, feeding rhythms and obesity in rodents." @default.
- W2000367437 created "2016-06-24" @default.
- W2000367437 creator A5067101808 @default.
- W2000367437 creator A5070474200 @default.
- W2000367437 date "2006-05-01" @default.
- W2000367437 modified "2023-10-17" @default.
- W2000367437 title "The hypothalamic H1 receptor: a novel therapeutic target for disrupting diurnal feeding rhythm and obesity" @default.
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- W2000367437 doi "https://doi.org/10.1016/j.tips.2006.03.008" @default.
- W2000367437 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16584790" @default.
- W2000367437 hasPublicationYear "2006" @default.
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