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• W2000369969 abstract "The neutropenia often seen in infants of hypetensive mothers (IHMs) at <12 hours of age has been associated with nosocomial infection in the first 18 days of life. To assess maternal hypertension as an independent factor for nosocomial infection, we compared 101 low birth weight (≤2.00 kg) IHMs to a concurrent birth weight—matched group of infants of normotensive mothers (IMMs). Infants without diferential leukocyte counts at <12 hours of age were excluded, leaving 93 IHMs and 98 INMs. The incidence of neutropenial at <12 hours among IHMs was not significantly different from that among INMs (42/95 (45%) vs 37/98 (38%)). Nosocomial infection was more frequent in neutropenic IHMs than in neutropenic INMs (12/42 vs 2/37; p=0.007). Infection in IHMs included omphalitis (2 Infants), pneumonia (4), and sepsis with or without meningitis (6); INMs had cellulitis (1) and sepsis (1). The underlying mechanism(s) for this predisposition remains to be elucidated, although limited data suggest that neutropenia may be more severe and prolonged among IHMs. The neutropenia often seen in infants of hypetensive mothers (IHMs) at <12 hours of age has been associated with nosocomial infection in the first 18 days of life. To assess maternal hypertension as an independent factor for nosocomial infection, we compared 101 low birth weight (≤2.00 kg) IHMs to a concurrent birth weight—matched group of infants of normotensive mothers (IMMs). Infants without diferential leukocyte counts at <12 hours of age were excluded, leaving 93 IHMs and 98 INMs. The incidence of neutropenial at <12 hours among IHMs was not significantly different from that among INMs (42/95 (45%) vs 37/98 (38%)). Nosocomial infection was more frequent in neutropenic IHMs than in neutropenic INMs (12/42 vs 2/37; p=0.007). Infection in IHMs included omphalitis (2 Infants), pneumonia (4), and sepsis with or without meningitis (6); INMs had cellulitis (1) and sepsis (1). The underlying mechanism(s) for this predisposition remains to be elucidated, although limited data suggest that neutropenia may be more severe and prolonged among IHMs." @default.
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• W2000369969 date "1992-12-01" @default.
• W2000369969 modified "2023-09-26" @default.
• W2000369969 title "Increased nosocomial infection in neutropenic low birth weight (2000 grams or less) infants of hypertensive mothers" @default.
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• W2000369969 doi "https://doi.org/10.1016/s0022-3476(05)80351-8" @default.
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