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- W2000371726 abstract "Solutions of nucleic acid bases, nucleosides and a nucleotide, saturated with either N2, N2O or O2, were irradiated and tested for mutagenicity towards Salmonella typhimurium, with and without pre-incubation. Irradiated solutions of the nucleic acid bases were all non-mutagenic. Irradiated solutions of the nucleosides showed mutagenicity in S. typhimurium TA100 (pre-incubation assay). Generally, the mutagenicity followed the order: N2O greater than N2 greater than O2. The results show that the formation of mutagenic radiolytic products is initiated by attack of mainly OH radicals on the 2-deoxy-D-ribose moiety of the nucleosides. With irradiated solutions of the nucleotide, thymidine-5'-monophosphate, no mutagenicity could be detected." @default.
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- W2000371726 date "1981-04-01" @default.
- W2000371726 modified "2023-10-14" @default.
- W2000371726 title "Mutagenicity of irradiated solutions of nucleic acid bases and nucleosides in Salmonella typhimurium" @default.
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- W2000371726 doi "https://doi.org/10.1016/0165-1218(81)90024-0" @default.
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