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- W2000372225 abstract "HeLa cells were implanted into athymic nude mice from tissue culture and solid tumors established (HeLa cell tumor or HCT). Large cell numbers of 1 X 10(7) were required to obtain consistent and progressive growth, and tumor growth followed a Gompertzian mode. Irradiation studies were carried out using acute Cobalt-60 (60Co), low-dose-rate (LDR) Cs-137 and LDR Cf-252. Cf-252, a neutron-emitting radioisotope, produced an immediate tumor shrinkage and regression response after a dose of 279 cGy. Acute 60Co or LDR Cs-137 irradiation with 1000 cGy had little effect on the HCT. After a dose of 2000 cGy of 60Co radiation tumor shrinkage followed a latent period of approximately 5 days. Cisplatin had no effect on the HCT in nude mice in stationary or late exponential growth." @default.
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- W2000372225 date "1984-07-15" @default.
- W2000372225 modified "2023-10-14" @default.
- W2000372225 title "HeLa cell tumor response to60Co, Cs-137, Cf-252 radiations and cisplatin chemotherapy in nude mice" @default.
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- W2000372225 doi "https://doi.org/10.1002/1097-0142(19840715)54:2<247::aid-cncr2820540211>3.0.co;2-7" @default.
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