Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000373871> ?p ?o ?g. }
- W2000373871 endingPage "220" @default.
- W2000373871 startingPage "214" @default.
- W2000373871 abstract "Abstract The effects of early antiretroviral therapy on the peripheral CD8+ T-cell population were assessed by sequentially determining the T-cell receptor (TCR) repertoire complexity in a cohort of 15 individuals recently diagnosed with human immunodeficiency virus infection. Analysis was based on quantitative TCR variable B gene (TCRBV) usage and complementary-determining region 3 length assessment. Repertories were assessed at baseline and at weeks 2, 4, 12, 24, and 72 after initiation of therapy. Early administration of highly active antiretroviral therapy has a positive effect on the preservation and homeostasis of the CD8+ cell repertoire. Nevertheless, differences from average baseline and control TCR profiles and initial development of repertoire perturbations were observed. The findings suggest that additional therapeutic protocols will be required during primary infection to significantly prevent long-term erosion of the T-cell–mediated immune response." @default.
- W2000373871 created "2016-06-24" @default.
- W2000373871 creator A5001149950 @default.
- W2000373871 creator A5032352295 @default.
- W2000373871 creator A5040530822 @default.
- W2000373871 creator A5041294204 @default.
- W2000373871 creator A5061011874 @default.
- W2000373871 creator A5077470394 @default.
- W2000373871 creator A5088568312 @default.
- W2000373871 date "2001-01-01" @default.
- W2000373871 modified "2023-10-16" @default.
- W2000373871 title "Longitudinal analysis of T-cell receptor gene use by CD8+ T cells in early human immunodeficiency virus infection in patients receiving highly active antiretroviral therapy" @default.
- W2000373871 cites W1013429822 @default.
- W2000373871 cites W1544655082 @default.
- W2000373871 cites W1574561647 @default.
- W2000373871 cites W1977542917 @default.
- W2000373871 cites W1999002546 @default.
- W2000373871 cites W2000980350 @default.
- W2000373871 cites W2005281007 @default.
- W2000373871 cites W2009905888 @default.
- W2000373871 cites W2012120988 @default.
- W2000373871 cites W2026615262 @default.
- W2000373871 cites W2037343680 @default.
- W2000373871 cites W2047269867 @default.
- W2000373871 cites W2051410330 @default.
- W2000373871 cites W2064279221 @default.
- W2000373871 cites W2085919513 @default.
- W2000373871 cites W2105381977 @default.
- W2000373871 cites W2108603500 @default.
- W2000373871 cites W2125170595 @default.
- W2000373871 cites W2129114331 @default.
- W2000373871 cites W2144365496 @default.
- W2000373871 cites W2144956326 @default.
- W2000373871 cites W2159773381 @default.
- W2000373871 cites W2161542073 @default.
- W2000373871 cites W2168932061 @default.
- W2000373871 cites W2315873899 @default.
- W2000373871 cites W2318289184 @default.
- W2000373871 cites W2323932292 @default.
- W2000373871 cites W2339219218 @default.
- W2000373871 cites W4211059834 @default.
- W2000373871 doi "https://doi.org/10.1182/blood.v97.1.214" @default.
- W2000373871 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11133763" @default.
- W2000373871 hasPublicationYear "2001" @default.
- W2000373871 type Work @default.
- W2000373871 sameAs 2000373871 @default.
- W2000373871 citedByCount "10" @default.
- W2000373871 countsByYear W20003738712014 @default.
- W2000373871 crossrefType "journal-article" @default.
- W2000373871 hasAuthorship W2000373871A5001149950 @default.
- W2000373871 hasAuthorship W2000373871A5032352295 @default.
- W2000373871 hasAuthorship W2000373871A5040530822 @default.
- W2000373871 hasAuthorship W2000373871A5041294204 @default.
- W2000373871 hasAuthorship W2000373871A5061011874 @default.
- W2000373871 hasAuthorship W2000373871A5077470394 @default.
- W2000373871 hasAuthorship W2000373871A5088568312 @default.
- W2000373871 hasBestOaLocation W20003738711 @default.
- W2000373871 hasConcept C121332964 @default.
- W2000373871 hasConcept C154317977 @default.
- W2000373871 hasConcept C159047783 @default.
- W2000373871 hasConcept C167672396 @default.
- W2000373871 hasConcept C19317047 @default.
- W2000373871 hasConcept C202751555 @default.
- W2000373871 hasConcept C203014093 @default.
- W2000373871 hasConcept C24890656 @default.
- W2000373871 hasConcept C2776090121 @default.
- W2000373871 hasConcept C2778473898 @default.
- W2000373871 hasConcept C2908647359 @default.
- W2000373871 hasConcept C54355233 @default.
- W2000373871 hasConcept C71924100 @default.
- W2000373871 hasConcept C86803240 @default.
- W2000373871 hasConcept C8891405 @default.
- W2000373871 hasConcept C99454951 @default.
- W2000373871 hasConceptScore W2000373871C121332964 @default.
- W2000373871 hasConceptScore W2000373871C154317977 @default.
- W2000373871 hasConceptScore W2000373871C159047783 @default.
- W2000373871 hasConceptScore W2000373871C167672396 @default.
- W2000373871 hasConceptScore W2000373871C19317047 @default.
- W2000373871 hasConceptScore W2000373871C202751555 @default.
- W2000373871 hasConceptScore W2000373871C203014093 @default.
- W2000373871 hasConceptScore W2000373871C24890656 @default.
- W2000373871 hasConceptScore W2000373871C2776090121 @default.
- W2000373871 hasConceptScore W2000373871C2778473898 @default.
- W2000373871 hasConceptScore W2000373871C2908647359 @default.
- W2000373871 hasConceptScore W2000373871C54355233 @default.
- W2000373871 hasConceptScore W2000373871C71924100 @default.
- W2000373871 hasConceptScore W2000373871C86803240 @default.
- W2000373871 hasConceptScore W2000373871C8891405 @default.
- W2000373871 hasConceptScore W2000373871C99454951 @default.
- W2000373871 hasIssue "1" @default.
- W2000373871 hasLocation W20003738711 @default.
- W2000373871 hasOpenAccess W2000373871 @default.
- W2000373871 hasPrimaryLocation W20003738711 @default.
- W2000373871 hasRelatedWork W1964323900 @default.
- W2000373871 hasRelatedWork W1976419594 @default.
- W2000373871 hasRelatedWork W2024351954 @default.
- W2000373871 hasRelatedWork W2063492259 @default.
- W2000373871 hasRelatedWork W2106875608 @default.