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- W2000374639 abstract "We have designed and synthesized a series of phosphorylated penta- and tri-peptides of general structures Rx-Glu-Glu-Ile-Glu and Rx-Glu-D-Trp-NH2, where Rx represents a phosphotyrosine mimetic. These peptides show binding affinity to pp60src SH2 domain in the micromolar range. Data are presented that provide an account of their structure-activity relationships and specificity properties. We have designed and synthesized a series of phosphorylated penta- and tri-peptides of general structures Rx-Glu-Glu-Ile-Glu and Rx-Glu-D-Trp-NH2, where Rx represents a phosphotyrosine mimetic. These peptides show binding affinity to pp60arc SH2 domain in the micromolar range. Data are presented that provide an account of their structure-activity relationships and specificity properties." @default.
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- W2000374639 date "1996-06-01" @default.
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- W2000374639 title "Novel phosphotyrosine mimetics in the design of peptide ligands for pp60src SH2 domain" @default.
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- W2000374639 doi "https://doi.org/10.1016/0960-894x(96)00208-9" @default.
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