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- W2000378384 abstract "Abstract Introduction The present work aimed to evaluate the antibacterial activity, phytochemical constituents, and cytotoxic effect of plant based remedies which are traditionally used for the treatment of infections. Methodology Antibacterial activity of the ethanol extracts of plant based preparations described in Thai Pharmaceutical Textbook namely: Tri-Khan-Tha-Wart, Tri-Ke-Son-Phet, Tri-Phit-Tha-Chak, Tri-Ka-Tuk, Tri-Pha-La, Tri-Kan-La-Phit, Tri-Chin-Tha-La-Ma-Ka, Tri-San, Tri-Sa-Mo, and Tri-Ke-Son-Mat were evaluated on 20 isolates of Gram-positive and Gram-negative pathogens. Qualitative phytochemical analysis and cytotoxic effect on Vero cells of the extracts were additionally performed. Results The extract of Tri-Chin-Tha-La-Ma-Ka possessed the highest and most significant antibacterial activity with minimum inhibitory concentration (MIC) values of 50 μg/mL on Vero cells, whereas Tri-Chin-Tha-La-Ma-Ka, Tri-Ka-Tuk, and Tri-Kan-La-Phit had IC50 value of 0.9, 48.8, and 28.9 μg/mL, respectively. Conclusion These findings suggest that Tri-Chin-Tha-La-Ma-Ka could be further studied as a promising antibacterial agent. Investigations on other biological activities related to its traditional applications, appropriate biomarkers, and treatment mechanisms of the preparation are required." @default.
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- W2000378384 date "2014-06-01" @default.
- W2000378384 modified "2023-09-27" @default.
- W2000378384 title "Assessments of antibacterial activity, phytochemical constituents, and cytotoxicity of herbal preparations used in Thailand" @default.
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- W2000378384 doi "https://doi.org/10.1016/j.eujim.2014.02.003" @default.
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