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• W2000379166 abstract "TheStaphylococcus epidermidisplasmid pSK639 is the prototype of a newly described family of small plasmids identified in clinical staphylococcal isolates. pSK639 is 8 kb in length and possesses a composite structure consisting of an IS257-flanked segment mediating trimethoprim resistance (Tpr), and regions responsible for replication and mobilization of the plasmid. Comparative sequence analysis suggests that a pSK639-like plasmid may represent a progenitor of previously identified staphylococcal Tprdeterminants related to the transposon-like structure, Tn4003.In contrast to the small staphylococcal plasmids characterized to date that all utilize a rolling circle mode of replication, the replication region of pSK639 was found to contain features typical of an iteron-controlled theta-mode replicon. pSK639 is the first small plasmid of this type to be identified in the staphylococci." @default.
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• W2000379166 date "1997-07-01" @default.
• W2000379166 modified "2023-09-25" @default.
• W2000379166 title "Molecular Analysis of a Mobilizable Theta-Mode Trimethoprim Resistance Plasmid from Coagulase-Negative Staphylococci" @default.
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• W2000379166 doi "https://doi.org/10.1006/plas.1997.1292" @default.
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