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• W2000381317 abstract "Length-regulation of microtubules (MTs) is essential for many cellular processes. Molecular motors like kinesin 8, which move along MTs and also act as depolymerases, are known as key players in MT dynamics. However, the regulatory mechanisms of length control remain elusive. Here, we investigate a stochastic model accounting for the interplay between polymerization kinetics and motor-induced depolymerization. We determine the dependence of MT length and variance on rate constants and motor concentration. Moreover, our analyses reveal how collective phenomena lead to a well-defined MT length." @default.
• W2000381317 created "2016-06-24" @default.
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• W2000381317 date "2012-06-22" @default.
• W2000381317 modified "2023-09-25" @default.
• W2000381317 title "Microtubule Length Regulation by Molecular Motors" @default.
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• W2000381317 doi "https://doi.org/10.1103/physrevlett.108.258104" @default.
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