Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000383643> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W2000383643 endingPage "S87" @default.
- W2000383643 startingPage "S87" @default.
- W2000383643 abstract "To investigate whether GnRH and TRH test during prepubertal period is useful for the diagnosis of gonadotropin deficiency in short children, 20 children (12 boys, 15.7±0.6 years old and 8 girls, 17.9±1.0 years old) were evaluated. All have received GH replacement according to the Japanese standard of assessment of short stature. Seven {4 boys and 3 girls} of the 20 children have multiple pituitary hormone deficiencies (MPHD) without the occurrence of puberty, who had been treated with thyroxine, cortisol and so on. Other 13 (8 boys and 5 girls) presumed to be isolated GH deficiency (IGHD) show normal pubertal development. The levels of LH, FSH and prolactin (PRL) on GnRH (2μg/kg) and TRH 10μg/kg) test during prepubertal period were compared between the MPHD and the IGHD. The chronological age when the tests were performed was at 9.8±0.9 years old in both groups. In boys, ΔFSH levels were decreased and basal PRL levels were increased in the MPHD as compared with those of the IGHD (0.9±0.4 vs 10.7±1.9 mIU/ml, 24.7±4.2 vs 12.5±2.5 ng/ml, respectively). In girls, basal LH and FSH, peak FSH and ΔFSH were decreased and basal PRL levels were increased in the MPHD as compared with those of the IGHD (3.6±0.9 vs 1.0±0.4 mIU/ml, 2.0±0.0 ve 3.8±0.3 mIU/ml, 5.2±2.5 vs 19.5±2.8 mIU/ml, 3.2±6.1 vs 15.7±2.5 mIU/ml, 19.0±3.0 vs 3.5±1.4 ng/ml, respectively). These results suggest that the subnormal response of gonadotropins to GnRH and the increased level of basal PRL might be an available index for the prediction of the absence of puberty in short children at adolescent age." @default.
- W2000383643 created "2016-06-24" @default.
- W2000383643 creator A5016055552 @default.
- W2000383643 creator A5042380592 @default.
- W2000383643 creator A5053187778 @default.
- W2000383643 creator A5060672769 @default.
- W2000383643 creator A5062775474 @default.
- W2000383643 creator A5076239306 @default.
- W2000383643 creator A5085437482 @default.
- W2000383643 date "1993-05-01" @default.
- W2000383643 modified "2023-10-18" @default.
- W2000383643 title "CAN GNRH AND TRH TEST DURING PREPUBERTAL PERIOD PREDICT THE OCCURRENCE OF PUBERTY IN SHORT CHILDREN?" @default.
- W2000383643 doi "https://doi.org/10.1203/00006450-199305001-00504" @default.
- W2000383643 hasPublicationYear "1993" @default.
- W2000383643 type Work @default.
- W2000383643 sameAs 2000383643 @default.
- W2000383643 citedByCount "0" @default.
- W2000383643 crossrefType "journal-article" @default.
- W2000383643 hasAuthorship W2000383643A5016055552 @default.
- W2000383643 hasAuthorship W2000383643A5042380592 @default.
- W2000383643 hasAuthorship W2000383643A5053187778 @default.
- W2000383643 hasAuthorship W2000383643A5060672769 @default.
- W2000383643 hasAuthorship W2000383643A5062775474 @default.
- W2000383643 hasAuthorship W2000383643A5076239306 @default.
- W2000383643 hasAuthorship W2000383643A5085437482 @default.
- W2000383643 hasBestOaLocation W20003836431 @default.
- W2000383643 hasConcept C126322002 @default.
- W2000383643 hasConcept C134018914 @default.
- W2000383643 hasConcept C2778024521 @default.
- W2000383643 hasConcept C2779064019 @default.
- W2000383643 hasConcept C2779306644 @default.
- W2000383643 hasConcept C2779430528 @default.
- W2000383643 hasConcept C2779952775 @default.
- W2000383643 hasConcept C2984496839 @default.
- W2000383643 hasConcept C71315377 @default.
- W2000383643 hasConcept C71924100 @default.
- W2000383643 hasConceptScore W2000383643C126322002 @default.
- W2000383643 hasConceptScore W2000383643C134018914 @default.
- W2000383643 hasConceptScore W2000383643C2778024521 @default.
- W2000383643 hasConceptScore W2000383643C2779064019 @default.
- W2000383643 hasConceptScore W2000383643C2779306644 @default.
- W2000383643 hasConceptScore W2000383643C2779430528 @default.
- W2000383643 hasConceptScore W2000383643C2779952775 @default.
- W2000383643 hasConceptScore W2000383643C2984496839 @default.
- W2000383643 hasConceptScore W2000383643C71315377 @default.
- W2000383643 hasConceptScore W2000383643C71924100 @default.
- W2000383643 hasLocation W20003836431 @default.
- W2000383643 hasOpenAccess W2000383643 @default.
- W2000383643 hasPrimaryLocation W20003836431 @default.
- W2000383643 hasRelatedWork W1975326514 @default.
- W2000383643 hasRelatedWork W1989830820 @default.
- W2000383643 hasRelatedWork W1997352238 @default.
- W2000383643 hasRelatedWork W2033209790 @default.
- W2000383643 hasRelatedWork W2072392368 @default.
- W2000383643 hasRelatedWork W2090359680 @default.
- W2000383643 hasRelatedWork W2093631943 @default.
- W2000383643 hasRelatedWork W2150096959 @default.
- W2000383643 hasRelatedWork W2152306407 @default.
- W2000383643 hasRelatedWork W2153052119 @default.
- W2000383643 hasVolume "33" @default.
- W2000383643 isParatext "false" @default.
- W2000383643 isRetracted "false" @default.
- W2000383643 magId "2000383643" @default.
- W2000383643 workType "article" @default.