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- W2000384235 abstract "A patient with intermittent left bundle branch block and moderate aortic insufficiency, presumably due to rheumatic heart disease, is presented. At retrograde left heart catheterization, left bundle branch block recurred repeatedly and was always converted to normal conduction and left ventricular hypertrophy by administration of oxygen. Electrocardiograms, intracardiac pressures and indicator-dilution curves for cardiac output were recorded with both types of conduction. The following hemodynamic alterations consistently accompanied intermittent left bundle branch block: 1. There was a significant fall in the systolic pressures in the left ventricle, central aorta and radial artery, a decreased stroke volume and an increased heart rate. These findings suggest that the force and intensity of left ventricular contraction and, consequently, systolic ejection are significantly decreased with the onset of delayed conduction. 2. A prolonged phase of isometric contraction was the most important alteration in the time relationships of the hemodynamic events of ventricular contraction. This resulted in delay in onset and termination of systolic ejection, with a normal duration of the ejection phase. Isometric relaxation was also prolonged proportionately, but duration of diastole shortened as the cardiac rate increased. Prolonged isometric contraction of the left ventricle is probably responsible for the delayed closure of the aortic valve and paradoxic or fixed splitting of the second heart sound very often seen with left bundle branch block." @default.
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- W2000384235 date "1962-12-01" @default.
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- W2000384235 title "Hemodynamic studies during intermittent left bundle branch block" @default.
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- W2000384235 doi "https://doi.org/10.1016/0002-9149(62)90173-x" @default.
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