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- W2000390216 abstract "In order to block acetylcholine receptors of muscle, the alpha toxin of the Formosan cobra (Naja naja atra) was given intravenously to rats. Electrophysiological and pharmacological changes typical of myasthenia gravis were recorded, including decremental responses to repetitive stimuli, curare sensitivity, neostigmine reversal, and posttetanic phenomena. This model supports the concept that a reduction of available acetylcholine receptors may play an important role in myasthenia gravis." @default.
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- W2000390216 date "1975-03-14" @default.
- W2000390216 modified "2023-10-18" @default.
- W2000390216 title "Blockade of Acetylcholine Receptors: A Model of Myasthenia Gravis" @default.
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- W2000390216 doi "https://doi.org/10.1126/science.1145181" @default.
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