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- W2000391438 abstract "Thirty-six healthy mature mice of both sexes were castrated bilaterally. Thereafter they were injected on alternate days with 10 mg each of vitamin E (“Juvela” prepared by Eisai Co. ) for 10to 60 days. Pituitaries obtained at various intervals were histologically examined and the results were as follows:With progress of the experiment, acidophiles s lightly increased in number accompanied by slight degranulation. Acidophiles with a conspicuous Golgi image, perinuclear halo and basophilic filamentous material RNA in nature were more frequently found than in the normal controls.Delta cells showed a slight increase in number. These cells mainly showed a degranulation and reacted feebly with PAS reagent and with anilin blue of azan stain.Theta cells rapidly decreased and disappeared with progress of the experiment.Beta cells and chromophobe cells did not show any appreciable change throughout this experimental period.The present data were generally s imilar to those of castrated control animals. From these observations, it was concluded that vitamin E administration does not alter significantly the castration changes in the mouse anterior pituitary.I wish to express my thanks to Prof. Dr. K. Yamada for his guidance and criticism throughout the course of this study." @default.
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- W2000391438 date "1960-01-01" @default.
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- W2000391438 title "Effects of Vitamin E Administration on the Anterior Pituitary of the Castrated Mouse" @default.
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- W2000391438 doi "https://doi.org/10.2535/ofaj1936.35.1-3_77" @default.
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