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• W2000392191 abstract "The lymphocytopenia that occurs during the recovery stage of exercise may be a result of apoptosis through an increased expression of CD95, a loss of the complement regulatory proteins CD55 and CD59, or both. Trained subjects completed intensive, moderate, and downhill treadmill-running protocols. Blood lymphocytes isolated before, immediately after, 1h after, and 24h after each exercise test were assessed for markers of apoptosis (Annexin-V+, HSP60+), and CD55, CD59, and CD95 expression by flow cytometry. Lymphocytopenia occurred 1h after intensive and downhill running exercise, but no changes in the percentage of Annexin-V + or HSP60 + lymphocytes were found. Numbers of CD95+, CD55dim, and CD59dim lymphocytes increased immediately after intensive and downhill exercise, which were attributed to the selective mobilization and subsequent efflux of CD8+ and CD56+ lymphocyte subsets. No differences were found between the intensive and downhill protocols. In conclusion, apoptosis of circulating lymphocytes does not appear to contribute to exercise-induced lymphocytopenia." @default.
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• W2000392191 date "2007-08-28" @default.
• W2000392191 modified "2023-09-27" @default.
• W2000392191 title "Apoptosis Does not Contribute to the Blood Lymphocytopenia Observed After Intensive and Downhill Treadmill Running in Humans" @default.
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• W2000392191 doi "https://doi.org/10.1080/15438620701405339" @default.
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