FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000392384> ?p ?o ?g. }

• W2000392384 endingPage "328" @default.
• W2000392384 startingPage "324" @default.
• W2000392384 abstract "To evaluate the efficacy of UDCA in arresting the progression of the early multifocal hepatic lesion to overt CF-related NBC.Focal biliary cirrhosis is an early hepatic pathologic change related to the ion transport defect in cystic fibrosis. The factors involved in the progression of focal to nodular biliary cirrhosis are not clear. Ursodeoxycholic--a hydrophilic, nontoxic, choleretic, and hepatoprotective exogenous bile acid--has been reported to be effective in the management of cholestatic liver disease.For 10 years at 6-month intervals, 70 individuals with cystic fibrosis (38 men and 32 women; age range, 2--29 years) were examined using hepatosplenomegaly, liver function tests, and ultrasound liver scan. Patients demonstrating evidence of liver involvement at the onset or during the study received ursodeoxycholic acid 20 mg/kg body weight.After the administration of ursodeoxycholic acid, the progression of nodular biliary cirrhosis ultrasound changes was arrested, hepatic function was preserved, and no variceal bleeding was observed. No case of focal biliary cirrhosis progressed to nodular biliary cirrhosis. Furthermore, the multifocal, multilobular changes suggestive of focal biliary cirrhosis on ultrasound scan were reversed to normal.Ursodeoxycholic acid is effective in improving cholestasis and hepatic dysfunction in nodular biliary cirrhosis and, also, in reversing the early sonography findings suggestive of focal biliary cirrhosis. It is speculated that ursodeoxycholic acid may prove to affect the natural history of cystic fibrosis-related liver disease." @default.
• W2000392384 created "2016-06-24" @default.
• W2000392384 creator A5012777864 @default.
• W2000392384 creator A5019670716 @default.
• W2000392384 creator A5027691621 @default.
• W2000392384 creator A5031329254 @default.
• W2000392384 creator A5046064305 @default.
• W2000392384 date "2001-04-01" @default.
• W2000392384 modified "2023-10-15" @default.
• W2000392384 title "Long-term Prospective Study of the Effect of Ursodeoxycholic Acid on Cystic Fibrosis-related Liver Disease" @default.
• W2000392384 cites W1630615775 @default.
• W2000392384 cites W1804108206 @default.
• W2000392384 cites W1922978848 @default.
• W2000392384 cites W1973115153 @default.
• W2000392384 cites W1981031030 @default.
• W2000392384 cites W1983686315 @default.
• W2000392384 cites W1992222323 @default.
• W2000392384 cites W2017711118 @default.
• W2000392384 cites W2022431735 @default.
• W2000392384 cites W2028807693 @default.
• W2000392384 cites W2029579643 @default.
• W2000392384 cites W2030747774 @default.
• W2000392384 cites W2036774130 @default.
• W2000392384 cites W2038899568 @default.
• W2000392384 cites W2040930814 @default.
• W2000392384 cites W2051227416 @default.
• W2000392384 cites W2051835488 @default.
• W2000392384 cites W2059678647 @default.
• W2000392384 cites W2062249117 @default.
• W2000392384 cites W2066848494 @default.
• W2000392384 cites W2070366391 @default.
• W2000392384 cites W2071394537 @default.
• W2000392384 cites W2072193478 @default.
• W2000392384 cites W2080053318 @default.
• W2000392384 cites W2084150266 @default.
• W2000392384 cites W2089597861 @default.
• W2000392384 cites W2092368009 @default.
• W2000392384 cites W2112816097 @default.
• W2000392384 cites W2116365881 @default.
• W2000392384 cites W2117126621 @default.
• W2000392384 cites W2125391335 @default.
• W2000392384 cites W2130143866 @default.
• W2000392384 cites W2172081684 @default.
• W2000392384 cites W2174527717 @default.
• W2000392384 cites W2417254063 @default.
• W2000392384 doi "https://doi.org/10.1097/00004836-200104000-00009" @default.
• W2000392384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11276276" @default.
• W2000392384 hasPublicationYear "2001" @default.
• W2000392384 type Work @default.
• W2000392384 sameAs 2000392384 @default.
• W2000392384 citedByCount "64" @default.
• W2000392384 countsByYear W20003923842012 @default.
• W2000392384 countsByYear W20003923842013 @default.
• W2000392384 countsByYear W20003923842014 @default.
• W2000392384 countsByYear W20003923842015 @default.
• W2000392384 countsByYear W20003923842016 @default.
• W2000392384 countsByYear W20003923842017 @default.
• W2000392384 countsByYear W20003923842019 @default.
• W2000392384 countsByYear W20003923842020 @default.
• W2000392384 countsByYear W20003923842021 @default.
• W2000392384 crossrefType "journal-article" @default.
• W2000392384 hasAuthorship W2000392384A5012777864 @default.
• W2000392384 hasAuthorship W2000392384A5019670716 @default.
• W2000392384 hasAuthorship W2000392384A5027691621 @default.
• W2000392384 hasAuthorship W2000392384A5031329254 @default.
• W2000392384 hasAuthorship W2000392384A5046064305 @default.
• W2000392384 hasConcept C126322002 @default.
• W2000392384 hasConcept C142724271 @default.
• W2000392384 hasConcept C2776938444 @default.
• W2000392384 hasConcept C2777075537 @default.
• W2000392384 hasConcept C2777214474 @default.
• W2000392384 hasConcept C2778593092 @default.
• W2000392384 hasConcept C2779075594 @default.
• W2000392384 hasConcept C2779134260 @default.
• W2000392384 hasConcept C2779399885 @default.
• W2000392384 hasConcept C2780366471 @default.
• W2000392384 hasConcept C2780965833 @default.
• W2000392384 hasConcept C2992208098 @default.
• W2000392384 hasConcept C2994419564 @default.
• W2000392384 hasConcept C71924100 @default.
• W2000392384 hasConcept C90924648 @default.
• W2000392384 hasConceptScore W2000392384C126322002 @default.
• W2000392384 hasConceptScore W2000392384C142724271 @default.
• W2000392384 hasConceptScore W2000392384C2776938444 @default.
• W2000392384 hasConceptScore W2000392384C2777075537 @default.
• W2000392384 hasConceptScore W2000392384C2777214474 @default.
• W2000392384 hasConceptScore W2000392384C2778593092 @default.
• W2000392384 hasConceptScore W2000392384C2779075594 @default.
• W2000392384 hasConceptScore W2000392384C2779134260 @default.
• W2000392384 hasConceptScore W2000392384C2779399885 @default.
• W2000392384 hasConceptScore W2000392384C2780366471 @default.
• W2000392384 hasConceptScore W2000392384C2780965833 @default.
• W2000392384 hasConceptScore W2000392384C2992208098 @default.
• W2000392384 hasConceptScore W2000392384C2994419564 @default.
• W2000392384 hasConceptScore W2000392384C71924100 @default.
• W2000392384 hasConceptScore W2000392384C90924648 @default.
• W2000392384 hasIssue "4" @default.
• W2000392384 hasLocation W20003923841 @default.

• next