FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000394672> ?p ?o ?g. }

• W2000394672 endingPage "176" @default.
• W2000394672 startingPage "171" @default.
• W2000394672 abstract "Abstract The whole-cell configuration of the patch-clamp technique was used to study voltage-gated K + conductances in retinal ganglion cells from postnatal rat. Retinal ganglion cells were fluorescently labeled in situ , dissociated from the retina, and maintained in culture. With physiological solutions in the bath and the pipette, depolarizing voltage steps from physiological holding potentials activated Na + -( I Na ), Ca 2+ ( I Ca ), and K + -currents studied previously in retinal ganglion cells. Here we report on a slowly decaying K + current, not heretofore reported in rat. With 4-AP, TEA, and Co 2+ in the bath, to block I A , I K , and I K(Ca) , respectively, a slowly decaying outward current was activated from —80 mV by steps positive to —40 mV. This current was present in 92% of all ganglion cells tested ( n = 83). It activated within 10 ms and inactivated with a voltage-independent time constant of about 70 ms at 35°C. Inactivation was voltage-dependent, half-maximal at —55 mV, and almost complete at 0 mV. The current was blocked by internal Cs + and TEA, or by external application of 1 mM Ba 2+ , but not by 3 mM extracellular Co 2+ . The biophysical and pharmacological properties of this current are distinctly different from those of slowly inactivating K + currents studied in other rat neurons. It was very similar, however, to a slowly inactivating K + current previously reported in ganglion cells of tiger salamander retina. This last finding indicates conservation of a defined K + channel type in functionally related cells in both lower vertebrates and mammals." @default.
• W2000394672 created "2016-06-24" @default.
• W2000394672 creator A5044747530 @default.
• W2000394672 creator A5066753734 @default.
• W2000394672 date "1992-02-01" @default.
• W2000394672 modified "2023-10-18" @default.
• W2000394672 title "A slowly inactivating K⁺ current in retinal ganglion cells from postnatal rat" @default.
• W2000394672 cites W1540820991 @default.
• W2000394672 cites W1730960125 @default.
• W2000394672 cites W1830737945 @default.
• W2000394672 cites W1970930847 @default.
• W2000394672 cites W1972046379 @default.
• W2000394672 cites W1976763631 @default.
• W2000394672 cites W1976877707 @default.
• W2000394672 cites W1979103094 @default.
• W2000394672 cites W1979569981 @default.
• W2000394672 cites W1993057350 @default.
• W2000394672 cites W1996071311 @default.
• W2000394672 cites W2009667219 @default.
• W2000394672 cites W2012318900 @default.
• W2000394672 cites W2027750445 @default.
• W2000394672 cites W2044858838 @default.
• W2000394672 cites W2049161238 @default.
• W2000394672 cites W2054106801 @default.
• W2000394672 cites W2054747517 @default.
• W2000394672 cites W2062963816 @default.
• W2000394672 cites W2076330297 @default.
• W2000394672 cites W2080928002 @default.
• W2000394672 cites W2137760362 @default.
• W2000394672 cites W2153847623 @default.
• W2000394672 cites W2163725582 @default.
• W2000394672 cites W2288331821 @default.
• W2000394672 cites W2484226452 @default.
• W2000394672 doi "https://doi.org/10.1017/s0952523800009330" @default.
• W2000394672 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1558829" @default.
• W2000394672 hasPublicationYear "1992" @default.
• W2000394672 type Work @default.
• W2000394672 sameAs 2000394672 @default.
• W2000394672 citedByCount "20" @default.
• W2000394672 countsByYear W20003946722012 @default.
• W2000394672 countsByYear W20003946722013 @default.
• W2000394672 countsByYear W20003946722019 @default.
• W2000394672 crossrefType "journal-article" @default.
• W2000394672 hasAuthorship W2000394672A5044747530 @default.
• W2000394672 hasAuthorship W2000394672A5066753734 @default.
• W2000394672 hasConcept C100837961 @default.
• W2000394672 hasConcept C105702510 @default.
• W2000394672 hasConcept C12554922 @default.
• W2000394672 hasConcept C133529732 @default.
• W2000394672 hasConcept C147944092 @default.
• W2000394672 hasConcept C169760540 @default.
• W2000394672 hasConcept C181911157 @default.
• W2000394672 hasConcept C185263204 @default.
• W2000394672 hasConcept C185592680 @default.
• W2000394672 hasConcept C2777093970 @default.
• W2000394672 hasConcept C2777624874 @default.
• W2000394672 hasConcept C2780827179 @default.
• W2000394672 hasConcept C2781334511 @default.
• W2000394672 hasConcept C28406088 @default.
• W2000394672 hasConcept C4141045 @default.
• W2000394672 hasConcept C55493867 @default.
• W2000394672 hasConcept C75323523 @default.
• W2000394672 hasConcept C79879829 @default.
• W2000394672 hasConcept C86803240 @default.
• W2000394672 hasConceptScore W2000394672C100837961 @default.
• W2000394672 hasConceptScore W2000394672C105702510 @default.
• W2000394672 hasConceptScore W2000394672C12554922 @default.
• W2000394672 hasConceptScore W2000394672C133529732 @default.
• W2000394672 hasConceptScore W2000394672C147944092 @default.
• W2000394672 hasConceptScore W2000394672C169760540 @default.
• W2000394672 hasConceptScore W2000394672C181911157 @default.
• W2000394672 hasConceptScore W2000394672C185263204 @default.
• W2000394672 hasConceptScore W2000394672C185592680 @default.
• W2000394672 hasConceptScore W2000394672C2777093970 @default.
• W2000394672 hasConceptScore W2000394672C2777624874 @default.
• W2000394672 hasConceptScore W2000394672C2780827179 @default.
• W2000394672 hasConceptScore W2000394672C2781334511 @default.
• W2000394672 hasConceptScore W2000394672C28406088 @default.
• W2000394672 hasConceptScore W2000394672C4141045 @default.
• W2000394672 hasConceptScore W2000394672C55493867 @default.
• W2000394672 hasConceptScore W2000394672C75323523 @default.
• W2000394672 hasConceptScore W2000394672C79879829 @default.
• W2000394672 hasConceptScore W2000394672C86803240 @default.
• W2000394672 hasIssue "2" @default.
• W2000394672 hasLocation W20003946721 @default.
• W2000394672 hasLocation W20003946722 @default.
• W2000394672 hasOpenAccess W2000394672 @default.
• W2000394672 hasPrimaryLocation W20003946721 @default.
• W2000394672 hasRelatedWork W111279135 @default.
• W2000394672 hasRelatedWork W1993774381 @default.
• W2000394672 hasRelatedWork W2024867507 @default.
• W2000394672 hasRelatedWork W2038825981 @default.
• W2000394672 hasRelatedWork W2055830121 @default.
• W2000394672 hasRelatedWork W2061630254 @default.
• W2000394672 hasRelatedWork W2068406497 @default.
• W2000394672 hasRelatedWork W2070607865 @default.
• W2000394672 hasRelatedWork W2078280030 @default.
• W2000394672 hasRelatedWork W2417181054 @default.

• next