FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000396646> ?p ?o ?g. }

• W2000396646 endingPage "2712" @default.
• W2000396646 startingPage "2707" @default.
• W2000396646 abstract "The invariant cell lineage and cell fate of Caenorhabditis elegans provide a unique opportunity to decode the molecular mechanisms of animal development. To exploit this opportunity, we have developed a system for automated cell lineage tracing during C. elegans embryogenesis, based on 3D, time-lapse imaging and automated image analysis. Using ubiquitously expressed histone-GFP fusion protein to label cells/nuclei and a confocal microscope, the imaging protocol captures embryogenesis at high spatial (31 planes at 1 microm apart) and temporal (every minute) resolution without apparent effects on development. A set of image analysis algorithms then automatically recognizes cells at each time point, tracks cell movements, divisions and deaths over time and assigns cell identities based on the canonical naming scheme. Starting from the four-cell stage (or earlier), our software, named starrynite, can trace the lineage up to the 350-cell stage in 25 min on a desktop computer. The few errors of automated lineaging can then be corrected in a few hours with a graphic interface that allows easy navigation of the images and the reported lineage tree. The system can be used to characterize lineage phenotypes of genes and/or extended to determine gene expression patterns in a living embryo at the single-cell level. We envision that this automation will make it practical to systematically decipher the developmental genes and pathways encoded in the genome of C. elegans." @default.
• W2000396646 created "2016-06-24" @default.
• W2000396646 creator A5012075534 @default.
• W2000396646 creator A5020154489 @default.
• W2000396646 creator A5048015824 @default.
• W2000396646 creator A5068842095 @default.
• W2000396646 creator A5070787487 @default.
• W2000396646 creator A5074206499 @default.
• W2000396646 date "2006-02-13" @default.
• W2000396646 modified "2023-10-01" @default.
• W2000396646 title "Automated cell lineage tracing in <i>Caenorhabditis elegans</i>" @default.
• W2000396646 cites W1564398126 @default.
• W2000396646 cites W1911220294 @default.
• W2000396646 cites W1976133790 @default.
• W2000396646 cites W1989952069 @default.
• W2000396646 cites W1994955455 @default.
• W2000396646 cites W2001481666 @default.
• W2000396646 cites W2035993805 @default.
• W2000396646 cites W2040516748 @default.
• W2000396646 cites W2043426556 @default.
• W2000396646 cites W2045397841 @default.
• W2000396646 cites W2047107948 @default.
• W2000396646 cites W2064145462 @default.
• W2000396646 cites W2064339093 @default.
• W2000396646 cites W2097376308 @default.
• W2000396646 cites W2110359316 @default.
• W2000396646 cites W2115734610 @default.
• W2000396646 cites W2133408521 @default.
• W2000396646 cites W2144953011 @default.
• W2000396646 cites W2152736493 @default.
• W2000396646 cites W2160938187 @default.
• W2000396646 cites W2166760188 @default.
• W2000396646 cites W4230501579 @default.
• W2000396646 cites W4248822856 @default.
• W2000396646 cites W4308665337 @default.
• W2000396646 doi "https://doi.org/10.1073/pnas.0511111103" @default.
• W2000396646 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1413828" @default.
• W2000396646 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16477039" @default.
• W2000396646 hasPublicationYear "2006" @default.
• W2000396646 type Work @default.
• W2000396646 sameAs 2000396646 @default.
• W2000396646 citedByCount "340" @default.
• W2000396646 countsByYear W20003966462012 @default.
• W2000396646 countsByYear W20003966462013 @default.
• W2000396646 countsByYear W20003966462014 @default.
• W2000396646 countsByYear W20003966462015 @default.
• W2000396646 countsByYear W20003966462016 @default.
• W2000396646 countsByYear W20003966462017 @default.
• W2000396646 countsByYear W20003966462018 @default.
• W2000396646 countsByYear W20003966462019 @default.
• W2000396646 countsByYear W20003966462020 @default.
• W2000396646 countsByYear W20003966462021 @default.
• W2000396646 countsByYear W20003966462022 @default.
• W2000396646 countsByYear W20003966462023 @default.
• W2000396646 crossrefType "journal-article" @default.
• W2000396646 hasAuthorship W2000396646A5012075534 @default.
• W2000396646 hasAuthorship W2000396646A5020154489 @default.
• W2000396646 hasAuthorship W2000396646A5048015824 @default.
• W2000396646 hasAuthorship W2000396646A5068842095 @default.
• W2000396646 hasAuthorship W2000396646A5070787487 @default.
• W2000396646 hasAuthorship W2000396646A5074206499 @default.
• W2000396646 hasBestOaLocation W20003966461 @default.
• W2000396646 hasConcept C104317684 @default.
• W2000396646 hasConcept C1491633281 @default.
• W2000396646 hasConcept C163952510 @default.
• W2000396646 hasConcept C2776817793 @default.
• W2000396646 hasConcept C2778944004 @default.
• W2000396646 hasConcept C54355233 @default.
• W2000396646 hasConcept C70721500 @default.
• W2000396646 hasConcept C85813293 @default.
• W2000396646 hasConcept C86339819 @default.
• W2000396646 hasConcept C86803240 @default.
• W2000396646 hasConceptScore W2000396646C104317684 @default.
• W2000396646 hasConceptScore W2000396646C1491633281 @default.
• W2000396646 hasConceptScore W2000396646C163952510 @default.
• W2000396646 hasConceptScore W2000396646C2776817793 @default.
• W2000396646 hasConceptScore W2000396646C2778944004 @default.
• W2000396646 hasConceptScore W2000396646C54355233 @default.
• W2000396646 hasConceptScore W2000396646C70721500 @default.
• W2000396646 hasConceptScore W2000396646C85813293 @default.
• W2000396646 hasConceptScore W2000396646C86339819 @default.
• W2000396646 hasConceptScore W2000396646C86803240 @default.
• W2000396646 hasIssue "8" @default.
• W2000396646 hasLocation W20003966461 @default.
• W2000396646 hasLocation W20003966462 @default.
• W2000396646 hasLocation W20003966463 @default.
• W2000396646 hasLocation W20003966464 @default.
• W2000396646 hasOpenAccess W2000396646 @default.
• W2000396646 hasPrimaryLocation W20003966461 @default.
• W2000396646 hasRelatedWork W1809349505 @default.
• W2000396646 hasRelatedWork W1920402565 @default.
• W2000396646 hasRelatedWork W1946787458 @default.
• W2000396646 hasRelatedWork W2006824440 @default.
• W2000396646 hasRelatedWork W2125731289 @default.
• W2000396646 hasRelatedWork W2141084979 @default.
• W2000396646 hasRelatedWork W2141932099 @default.
• W2000396646 hasRelatedWork W2157166663 @default.
• W2000396646 hasRelatedWork W2761395833 @default.

• next