Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000398538> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2000398538 endingPage "831" @default.
- W2000398538 startingPage "826" @default.
- W2000398538 abstract "Ouabain-resistant Na and Li effluxes in erythrocytes from 18 normal subjects and 19 hypertensive subjects were studied in fresh cells that contained about 9 mmol Li and 2.5 or 6.5 mmol Na per liter of erythrocytes after intact cells had been incubated for 5 hours in 110 mM Li, 40 mM Na medium, with or without ouabain 10(-4) M. Outward Na cotransport was estimated at both internal Na concentrations as the furosemide-sensitive unidirectional 22Na efflux from erythrocytes into a Na free-medium containing 75 mM MgCl2. The changes in furosemide-sensitive outward Na transport between the two levels of internal Na were considered as a measure of the response of Na cotransport to the changes in internal Na within its physiological range. At both levels of internal Na, outward Na cotransport was reduced in the majority but not in all of the patients with essential hypertension (p less than 0.05 at 2.5 mmol; p less than 0.001 at 6.5 mmol). The ratio of the changes in Na cotransport to those in internal Na was lower in the hypertensive patients than in the control subjects (17.2 mumol/liter red blood cells/hr/1 mmol in internal Na increase vs 42.2, p less than 0.001). The Li-Na countertransport was increased in a few patients with essential hypertension, with no relationship to cotransport. We conclude that, in essential hypertension, the outward Na + K cotransport is impaired in fresh erythrocytes not treated with PCMBS (2,5 p-chloromercuribenzene sulfonate) or nystatin, even when internal Na is around its physiological range." @default.
- W2000398538 created "2016-06-24" @default.
- W2000398538 creator A5002766884 @default.
- W2000398538 creator A5035567247 @default.
- W2000398538 creator A5037384612 @default.
- W2000398538 creator A5046738682 @default.
- W2000398538 creator A5058029847 @default.
- W2000398538 creator A5076720727 @default.
- W2000398538 creator A5083788793 @default.
- W2000398538 date "1984-11-01" @default.
- W2000398538 modified "2023-09-26" @default.
- W2000398538 title "Low sodium cotransport in red cells with physiological internal sodium concentration in essential hypertension." @default.
- W2000398538 cites W1494889398 @default.
- W2000398538 cites W1971172114 @default.
- W2000398538 cites W1979002671 @default.
- W2000398538 cites W2002049568 @default.
- W2000398538 cites W2016261268 @default.
- W2000398538 cites W2018633989 @default.
- W2000398538 cites W2035171730 @default.
- W2000398538 cites W2040241441 @default.
- W2000398538 cites W2041386649 @default.
- W2000398538 cites W2051824192 @default.
- W2000398538 cites W2052478831 @default.
- W2000398538 cites W2057654580 @default.
- W2000398538 cites W2061063592 @default.
- W2000398538 cites W2062915771 @default.
- W2000398538 cites W2069617963 @default.
- W2000398538 cites W2083236965 @default.
- W2000398538 cites W2085032760 @default.
- W2000398538 cites W2095220978 @default.
- W2000398538 cites W2096595229 @default.
- W2000398538 cites W2121020585 @default.
- W2000398538 cites W2126809650 @default.
- W2000398538 cites W2130719907 @default.
- W2000398538 cites W2152524846 @default.
- W2000398538 cites W2340550980 @default.
- W2000398538 doi "https://doi.org/10.1161/01.hyp.6.6.826" @default.
- W2000398538 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6097541" @default.
- W2000398538 hasPublicationYear "1984" @default.
- W2000398538 type Work @default.
- W2000398538 sameAs 2000398538 @default.
- W2000398538 citedByCount "7" @default.
- W2000398538 crossrefType "journal-article" @default.
- W2000398538 hasAuthorship W2000398538A5002766884 @default.
- W2000398538 hasAuthorship W2000398538A5035567247 @default.
- W2000398538 hasAuthorship W2000398538A5037384612 @default.
- W2000398538 hasAuthorship W2000398538A5046738682 @default.
- W2000398538 hasAuthorship W2000398538A5058029847 @default.
- W2000398538 hasAuthorship W2000398538A5076720727 @default.
- W2000398538 hasAuthorship W2000398538A5083788793 @default.
- W2000398538 hasConcept C126322002 @default.
- W2000398538 hasConcept C134018914 @default.
- W2000398538 hasConcept C176674119 @default.
- W2000398538 hasConcept C178790620 @default.
- W2000398538 hasConcept C185592680 @default.
- W2000398538 hasConcept C188053792 @default.
- W2000398538 hasConcept C2776557347 @default.
- W2000398538 hasConcept C2777097880 @default.
- W2000398538 hasConcept C2777955127 @default.
- W2000398538 hasConcept C2779133857 @default.
- W2000398538 hasConcept C537181965 @default.
- W2000398538 hasConcept C55493867 @default.
- W2000398538 hasConcept C71924100 @default.
- W2000398538 hasConcept C84393581 @default.
- W2000398538 hasConceptScore W2000398538C126322002 @default.
- W2000398538 hasConceptScore W2000398538C134018914 @default.
- W2000398538 hasConceptScore W2000398538C176674119 @default.
- W2000398538 hasConceptScore W2000398538C178790620 @default.
- W2000398538 hasConceptScore W2000398538C185592680 @default.
- W2000398538 hasConceptScore W2000398538C188053792 @default.
- W2000398538 hasConceptScore W2000398538C2776557347 @default.
- W2000398538 hasConceptScore W2000398538C2777097880 @default.
- W2000398538 hasConceptScore W2000398538C2777955127 @default.
- W2000398538 hasConceptScore W2000398538C2779133857 @default.
- W2000398538 hasConceptScore W2000398538C537181965 @default.
- W2000398538 hasConceptScore W2000398538C55493867 @default.
- W2000398538 hasConceptScore W2000398538C71924100 @default.
- W2000398538 hasConceptScore W2000398538C84393581 @default.
- W2000398538 hasIssue "6_pt_1" @default.
- W2000398538 hasLocation W20003985381 @default.
- W2000398538 hasLocation W20003985382 @default.
- W2000398538 hasOpenAccess W2000398538 @default.
- W2000398538 hasPrimaryLocation W20003985381 @default.
- W2000398538 hasRelatedWork W1988914568 @default.
- W2000398538 hasRelatedWork W1998643509 @default.
- W2000398538 hasRelatedWork W2000398538 @default.
- W2000398538 hasRelatedWork W2004379323 @default.
- W2000398538 hasRelatedWork W2016261268 @default.
- W2000398538 hasRelatedWork W2057309019 @default.
- W2000398538 hasRelatedWork W2131024538 @default.
- W2000398538 hasRelatedWork W2340550980 @default.
- W2000398538 hasRelatedWork W2414103222 @default.
- W2000398538 hasRelatedWork W2415635415 @default.
- W2000398538 hasVolume "6" @default.
- W2000398538 isParatext "false" @default.
- W2000398538 isRetracted "false" @default.
- W2000398538 magId "2000398538" @default.
- W2000398538 workType "article" @default.