FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000400807> ?p ?o ?g. }

• W2000400807 endingPage "128" @default.
• W2000400807 startingPage "120" @default.
• W2000400807 abstract "A stoichiometric model describing the central metabolism of Shewanella oneidensis MR-1 wild-type and derivative strains was developed and used in elementary mode analysis (EMA). Shewanella oneidensis MR-1 can anaerobically respire a diverse pool of electron acceptors, and may be applied in several biotechnology settings, including bioremediation of toxic metals, electricity generation in microbial fuel cells, and whole-cell biocatalysis. The metabolic model presented here was adapted and verified by comparing the growth phenotypes of 13 single- and 1 double-knockout strains, while considering respiration via aerobic, anaerobic fumarate, and anaerobic metal reduction (Mtr) pathways, and utilizing acetate, n-acetylglucosamine (NAG), or lactate as carbon sources. The gene ppc, which encodes phosphoenolpyruvate carboxylase (Ppc), was determined to be necessary for aerobic growth on NAG and lactate, while not essential for growth on acetate. This suggests that Ppc is the only active anaplerotic enzyme when cultivated on lactate and NAG. The application of regulatory and substrate limitations to EMA has enabled creation of metabolic models that better reflect biological conditions, and significantly reduce the solution space for each condition, facilitating rapid strain optimization. This wild-type model can be easily adapted to include utilization of different carbon sources or secretion of different metabolic products, and allows the prediction of single- and multiple-knockout strains that are expected to operate under defined conditions with increased efficiency when compared to wild type cells." @default.
• W2000400807 created "2016-06-24" @default.
• W2000400807 creator A5005698632 @default.
• W2000400807 creator A5017784949 @default.
• W2000400807 creator A5024579365 @default.
• W2000400807 creator A5031834713 @default.
• W2000400807 date "2012-02-01" @default.
• W2000400807 modified "2023-10-13" @default.
• W2000400807 title "Construction and elementary mode analysis of a metabolic model for Shewanella oneidensis MR-1" @default.
• W2000400807 cites W1514995899 @default.
• W2000400807 cites W1585229154 @default.
• W2000400807 cites W1807981783 @default.
• W2000400807 cites W1949588586 @default.
• W2000400807 cites W1964491374 @default.
• W2000400807 cites W1967398671 @default.
• W2000400807 cites W1989277878 @default.
• W2000400807 cites W2006028467 @default.
• W2000400807 cites W2023716424 @default.
• W2000400807 cites W2028681077 @default.
• W2000400807 cites W2029058413 @default.
• W2000400807 cites W2037838434 @default.
• W2000400807 cites W2042970522 @default.
• W2000400807 cites W2045780029 @default.
• W2000400807 cites W2049092556 @default.
• W2000400807 cites W2057355720 @default.
• W2000400807 cites W2058529944 @default.
• W2000400807 cites W2065095031 @default.
• W2000400807 cites W2083693802 @default.
• W2000400807 cites W2091793452 @default.
• W2000400807 cites W2094399313 @default.
• W2000400807 cites W2098954147 @default.
• W2000400807 cites W2099039198 @default.
• W2000400807 cites W2099928613 @default.
• W2000400807 cites W2104785052 @default.
• W2000400807 cites W2115091055 @default.
• W2000400807 cites W2116735729 @default.
• W2000400807 cites W2123102279 @default.
• W2000400807 cites W2123783604 @default.
• W2000400807 cites W2130153222 @default.
• W2000400807 cites W2131111260 @default.
• W2000400807 cites W2139417409 @default.
• W2000400807 cites W2148274908 @default.
• W2000400807 cites W2149110469 @default.
• W2000400807 cites W2149568956 @default.
• W2000400807 cites W2153629132 @default.
• W2000400807 cites W2158069895 @default.
• W2000400807 cites W2158784643 @default.
• W2000400807 cites W4235920957 @default.
• W2000400807 doi "https://doi.org/10.1016/j.biosystems.2011.10.003" @default.
• W2000400807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22024451" @default.
• W2000400807 hasPublicationYear "2012" @default.
• W2000400807 type Work @default.
• W2000400807 sameAs 2000400807 @default.
• W2000400807 citedByCount "32" @default.
• W2000400807 countsByYear W20004008072012 @default.
• W2000400807 countsByYear W20004008072013 @default.
• W2000400807 countsByYear W20004008072014 @default.
• W2000400807 countsByYear W20004008072015 @default.
• W2000400807 countsByYear W20004008072016 @default.
• W2000400807 countsByYear W20004008072017 @default.
• W2000400807 countsByYear W20004008072018 @default.
• W2000400807 countsByYear W20004008072019 @default.
• W2000400807 countsByYear W20004008072020 @default.
• W2000400807 countsByYear W20004008072021 @default.
• W2000400807 countsByYear W20004008072022 @default.
• W2000400807 crossrefType "journal-article" @default.
• W2000400807 hasAuthorship W2000400807A5005698632 @default.
• W2000400807 hasAuthorship W2000400807A5017784949 @default.
• W2000400807 hasAuthorship W2000400807A5024579365 @default.
• W2000400807 hasAuthorship W2000400807A5031834713 @default.
• W2000400807 hasConcept C111341932 @default.
• W2000400807 hasConcept C143937172 @default.
• W2000400807 hasConcept C147789679 @default.
• W2000400807 hasConcept C165337572 @default.
• W2000400807 hasConcept C17525397 @default.
• W2000400807 hasConcept C181199279 @default.
• W2000400807 hasConcept C185592680 @default.
• W2000400807 hasConcept C2778824058 @default.
• W2000400807 hasConcept C2781170380 @default.
• W2000400807 hasConcept C2900893 @default.
• W2000400807 hasConcept C523546767 @default.
• W2000400807 hasConcept C54355233 @default.
• W2000400807 hasConcept C55493867 @default.
• W2000400807 hasConcept C86803240 @default.
• W2000400807 hasConcept C89395315 @default.
• W2000400807 hasConceptScore W2000400807C111341932 @default.
• W2000400807 hasConceptScore W2000400807C143937172 @default.
• W2000400807 hasConceptScore W2000400807C147789679 @default.
• W2000400807 hasConceptScore W2000400807C165337572 @default.
• W2000400807 hasConceptScore W2000400807C17525397 @default.
• W2000400807 hasConceptScore W2000400807C181199279 @default.
• W2000400807 hasConceptScore W2000400807C185592680 @default.
• W2000400807 hasConceptScore W2000400807C2778824058 @default.
• W2000400807 hasConceptScore W2000400807C2781170380 @default.
• W2000400807 hasConceptScore W2000400807C2900893 @default.
• W2000400807 hasConceptScore W2000400807C523546767 @default.
• W2000400807 hasConceptScore W2000400807C54355233 @default.
• W2000400807 hasConceptScore W2000400807C55493867 @default.

• next