FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000406054> ?p ?o ?g. }

• W2000406054 endingPage "H1624" @default.
• W2000406054 startingPage "H1618" @default.
• W2000406054 abstract "The dose- and time dependence of melatonin and the effective window of melatonin administration were determined in a mouse model of myocardial infarction. When mouse hearts were subjected to 60 min of occlusion of the left anterior descending artery (LAD) followed by 4 h of reperfusion, melatonin pretreatment for 30 min significantly reduced the infarct size/risk area. The most effective dose was found to be 150 μg/kg intraperitoneally, and the effective period of protection lasted up to 2 h after melatonin administration. Melatonin administration 45 min after LAD ligation or right before reperfusion was as effective as administration 30 min before ligation; however, melatonin administered after the release of occlusion was not protective. Melatonin's effect was still present in mice deficient for the Mel1a melatonin receptor. 8-Methoxy-2-propionamidotetralin, a melatonin receptor agonist with no antioxidant activity, offered no protection, suggesting a lack of involvement of melatonin receptors. Finally, the effects of melatonin were similar in rats and mice. Our results demonstrate that melatonin is an effective cardioprotective agent when administered either before or during coronary occlusion at a very low dose." @default.
• W2000406054 created "2016-06-24" @default.
• W2000406054 creator A5000200373 @default.
• W2000406054 creator A5011207006 @default.
• W2000406054 creator A5033745056 @default.
• W2000406054 creator A5078989269 @default.
• W2000406054 creator A5080891161 @default.
• W2000406054 date "2003-05-01" @default.
• W2000406054 modified "2023-10-17" @default.
• W2000406054 title "Protective effect of melatonin on myocardial infarction" @default.
• W2000406054 cites W1511779378 @default.
• W2000406054 cites W1975025234 @default.
• W2000406054 cites W1977014734 @default.
• W2000406054 cites W1983837006 @default.
• W2000406054 cites W2000874404 @default.
• W2000406054 cites W2002912123 @default.
• W2000406054 cites W2004851058 @default.
• W2000406054 cites W2018032623 @default.
• W2000406054 cites W2019320745 @default.
• W2000406054 cites W2019955714 @default.
• W2000406054 cites W2020621453 @default.
• W2000406054 cites W2025243629 @default.
• W2000406054 cites W2037024495 @default.
• W2000406054 cites W2044908790 @default.
• W2000406054 cites W2045644996 @default.
• W2000406054 cites W2058232887 @default.
• W2000406054 cites W2058973159 @default.
• W2000406054 cites W2065640295 @default.
• W2000406054 cites W2067184705 @default.
• W2000406054 cites W2070839245 @default.
• W2000406054 cites W2070905448 @default.
• W2000406054 cites W2080668150 @default.
• W2000406054 cites W2085651394 @default.
• W2000406054 cites W2094082830 @default.
• W2000406054 cites W2099787261 @default.
• W2000406054 cites W2111139290 @default.
• W2000406054 cites W2122846770 @default.
• W2000406054 cites W2139251967 @default.
• W2000406054 cites W2165280518 @default.
• W2000406054 cites W2329963186 @default.
• W2000406054 cites W2427930196 @default.
• W2000406054 doi "https://doi.org/10.1152/ajpheart.00874.2002" @default.
• W2000406054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12679327" @default.
• W2000406054 hasPublicationYear "2003" @default.
• W2000406054 type Work @default.
• W2000406054 sameAs 2000406054 @default.
• W2000406054 citedByCount "46" @default.
• W2000406054 countsByYear W20004060542012 @default.
• W2000406054 countsByYear W20004060542013 @default.
• W2000406054 countsByYear W20004060542014 @default.
• W2000406054 countsByYear W20004060542016 @default.
• W2000406054 countsByYear W20004060542017 @default.
• W2000406054 countsByYear W20004060542018 @default.
• W2000406054 countsByYear W20004060542020 @default.
• W2000406054 countsByYear W20004060542021 @default.
• W2000406054 countsByYear W20004060542022 @default.
• W2000406054 crossrefType "journal-article" @default.
• W2000406054 hasAuthorship W2000406054A5000200373 @default.
• W2000406054 hasAuthorship W2000406054A5011207006 @default.
• W2000406054 hasAuthorship W2000406054A5033745056 @default.
• W2000406054 hasAuthorship W2000406054A5078989269 @default.
• W2000406054 hasAuthorship W2000406054A5080891161 @default.
• W2000406054 hasConcept C126322002 @default.
• W2000406054 hasConcept C134018914 @default.
• W2000406054 hasConcept C170493617 @default.
• W2000406054 hasConcept C179437574 @default.
• W2000406054 hasConcept C2776268601 @default.
• W2000406054 hasConcept C2777798775 @default.
• W2000406054 hasConcept C2778182776 @default.
• W2000406054 hasConcept C2778938600 @default.
• W2000406054 hasConcept C2780393670 @default.
• W2000406054 hasConcept C2781269140 @default.
• W2000406054 hasConcept C42219234 @default.
• W2000406054 hasConcept C500558357 @default.
• W2000406054 hasConcept C71924100 @default.
• W2000406054 hasConcept C98274493 @default.
• W2000406054 hasConceptScore W2000406054C126322002 @default.
• W2000406054 hasConceptScore W2000406054C134018914 @default.
• W2000406054 hasConceptScore W2000406054C170493617 @default.
• W2000406054 hasConceptScore W2000406054C179437574 @default.
• W2000406054 hasConceptScore W2000406054C2776268601 @default.
• W2000406054 hasConceptScore W2000406054C2777798775 @default.
• W2000406054 hasConceptScore W2000406054C2778182776 @default.
• W2000406054 hasConceptScore W2000406054C2778938600 @default.
• W2000406054 hasConceptScore W2000406054C2780393670 @default.
• W2000406054 hasConceptScore W2000406054C2781269140 @default.
• W2000406054 hasConceptScore W2000406054C42219234 @default.
• W2000406054 hasConceptScore W2000406054C500558357 @default.
• W2000406054 hasConceptScore W2000406054C71924100 @default.
• W2000406054 hasConceptScore W2000406054C98274493 @default.
• W2000406054 hasIssue "5" @default.
• W2000406054 hasLocation W20004060541 @default.
• W2000406054 hasLocation W20004060542 @default.
• W2000406054 hasOpenAccess W2000406054 @default.
• W2000406054 hasPrimaryLocation W20004060541 @default.
• W2000406054 hasRelatedWork W1980207544 @default.
• W2000406054 hasRelatedWork W1999707698 @default.
• W2000406054 hasRelatedWork W2009692691 @default.

• next