FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000408858> ?p ?o ?g. }

• W2000408858 endingPage "330" @default.
• W2000408858 startingPage "324" @default.
• W2000408858 abstract "The c-myc oncogene status was determined in patients with nondysplasia (ND; 9 patients), low-grade squamous intraepithelial lesion (LGSIL; 12 patients), high-grade squamous intraepithelial lesion (HGSIL; 21 patients) and invasive squamous cell carcinoma (ISCC; 20 patients) of uterine cervix using fluorescent quantitative polymerase chain reaction (PCR). In the same paraffin-embedded specimens, other potential risk factors were also screened: human papillomavirus (HPV) infection, Ha-ras codon 12 mutation, DNA aneuploidy. Gene amplification, identified as c-myc copy numbers greater than the mean value +2 SD of patients with ND, was seen in 44% patients with LGSIL, 76% patients with HGSIL, and 67% patients with ISCC. These data indicate that c-myc amplification is one of the critical early events in the progression of uterine cervical lesions. HPV infection of various subtypes was identified in 0% patients with ND, 55% patients with LGSIL, 95% patients with HGSIL, and 84% patients with ISCC. No codon 12 mutation of the Ha-ras gene was found in this series. Aneuploid DNA pattern was seen in 0% patients with ND, 58% patients with LGSIL, 90% patients with HGSIL, and 80% patients with ISCC. There was a significant correlation between HPV infection and DNA aneuploidy. However, no relationship was seen between c-myc status and other factors in this series. Patients with HGSIL and ISCC almost always (95%) had multiple risk factors, whereas more than half of the patients with LGSIL had no or only one risk factor (P = 0.0001)." @default.
• W2000408858 created "2016-06-24" @default.
• W2000408858 creator A5017409069 @default.
• W2000408858 creator A5037450592 @default.
• W2000408858 creator A5043350681 @default.
• W2000408858 creator A5043590671 @default.
• W2000408858 creator A5047969795 @default.
• W2000408858 date "1998-12-01" @default.
• W2000408858 modified "2023-09-27" @default.
• W2000408858 title "Uterine Cervical Dysplasia and Cancer" @default.
• W2000408858 cites W1963897111 @default.
• W2000408858 cites W1983927889 @default.
• W2000408858 cites W2001258296 @default.
• W2000408858 cites W2006368702 @default.
• W2000408858 cites W2008415422 @default.
• W2000408858 cites W2016456425 @default.
• W2000408858 cites W2018075841 @default.
• W2000408858 cites W2018733832 @default.
• W2000408858 cites W2034070407 @default.
• W2000408858 cites W2038500217 @default.
• W2000408858 cites W2039382131 @default.
• W2000408858 cites W2060786724 @default.
• W2000408858 cites W2080223116 @default.
• W2000408858 cites W2084293249 @default.
• W2000408858 cites W2086723217 @default.
• W2000408858 cites W2101368305 @default.
• W2000408858 cites W2105258907 @default.
• W2000408858 cites W2140100637 @default.
• W2000408858 cites W2144972076 @default.
• W2000408858 cites W2158638762 @default.
• W2000408858 cites W3007238751 @default.
• W2000408858 cites W4301333013 @default.
• W2000408858 cites W51112460 @default.
• W2000408858 doi "https://doi.org/10.1097/00019606-199812000-00006" @default.
• W2000408858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10207671" @default.
• W2000408858 hasPublicationYear "1998" @default.
• W2000408858 type Work @default.
• W2000408858 sameAs 2000408858 @default.
• W2000408858 citedByCount "30" @default.
• W2000408858 countsByYear W20004088582012 @default.
• W2000408858 countsByYear W20004088582013 @default.
• W2000408858 countsByYear W20004088582014 @default.
• W2000408858 countsByYear W20004088582019 @default.
• W2000408858 crossrefType "journal-article" @default.
• W2000408858 hasAuthorship W2000408858A5017409069 @default.
• W2000408858 hasAuthorship W2000408858A5037450592 @default.
• W2000408858 hasAuthorship W2000408858A5043350681 @default.
• W2000408858 hasAuthorship W2000408858A5043590671 @default.
• W2000408858 hasAuthorship W2000408858A5047969795 @default.
• W2000408858 hasConcept C104317684 @default.
• W2000408858 hasConcept C121608353 @default.
• W2000408858 hasConcept C126322002 @default.
• W2000408858 hasConcept C142724271 @default.
• W2000408858 hasConcept C174618031 @default.
• W2000408858 hasConcept C2775924586 @default.
• W2000408858 hasConcept C2776511402 @default.
• W2000408858 hasConcept C2777083264 @default.
• W2000408858 hasConcept C2777343196 @default.
• W2000408858 hasConcept C2777740455 @default.
• W2000408858 hasConcept C2778220009 @default.
• W2000408858 hasConcept C2781156865 @default.
• W2000408858 hasConcept C49105822 @default.
• W2000408858 hasConcept C54355233 @default.
• W2000408858 hasConcept C59822182 @default.
• W2000408858 hasConcept C71924100 @default.
• W2000408858 hasConcept C86803240 @default.
• W2000408858 hasConcept C90924648 @default.
• W2000408858 hasConceptScore W2000408858C104317684 @default.
• W2000408858 hasConceptScore W2000408858C121608353 @default.
• W2000408858 hasConceptScore W2000408858C126322002 @default.
• W2000408858 hasConceptScore W2000408858C142724271 @default.
• W2000408858 hasConceptScore W2000408858C174618031 @default.
• W2000408858 hasConceptScore W2000408858C2775924586 @default.
• W2000408858 hasConceptScore W2000408858C2776511402 @default.
• W2000408858 hasConceptScore W2000408858C2777083264 @default.
• W2000408858 hasConceptScore W2000408858C2777343196 @default.
• W2000408858 hasConceptScore W2000408858C2777740455 @default.
• W2000408858 hasConceptScore W2000408858C2778220009 @default.
• W2000408858 hasConceptScore W2000408858C2781156865 @default.
• W2000408858 hasConceptScore W2000408858C49105822 @default.
• W2000408858 hasConceptScore W2000408858C54355233 @default.
• W2000408858 hasConceptScore W2000408858C59822182 @default.
• W2000408858 hasConceptScore W2000408858C71924100 @default.
• W2000408858 hasConceptScore W2000408858C86803240 @default.
• W2000408858 hasConceptScore W2000408858C90924648 @default.
• W2000408858 hasIssue "6" @default.
• W2000408858 hasLocation W20004088581 @default.
• W2000408858 hasLocation W20004088582 @default.
• W2000408858 hasOpenAccess W2000408858 @default.
• W2000408858 hasPrimaryLocation W20004088581 @default.
• W2000408858 hasRelatedWork W1564334751 @default.
• W2000408858 hasRelatedWork W2182411120 @default.
• W2000408858 hasRelatedWork W2361027325 @default.
• W2000408858 hasRelatedWork W2389353389 @default.
• W2000408858 hasRelatedWork W2514884906 @default.
• W2000408858 hasRelatedWork W2622361861 @default.
• W2000408858 hasRelatedWork W2919061549 @default.
• W2000408858 hasRelatedWork W2952932281 @default.

• next