Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000409284> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W2000409284 endingPage "226" @default.
- W2000409284 startingPage "213" @default.
- W2000409284 abstract "Monoclonal antibodies (MoAbs) reacting with bovine leukocyte membrane antigens have been prepared by fusion of mouse myeloma cells (SP2/0.Ag.14) and spleen cells of mice immunized with various cell types. Three of these MoAbs detected membrane components showing the typical structure of class I MHC molecules; indeed, immunoprecipitation studies revealed that these components were proteins composed of two subunits of 44,000 and 12,000 daltons apparent molecular weight. The density of these antigens in the cells of various leukocyte lineages was determined by solid phase radioimmunoassay, immunogold staining and cytofluorometry. Their expression seemed similar to that of class I molecules in other species, namely heavy on the mononuclear blood cells and weaker on the neutrophils and platelets. The eosinophils appeared more positive than the neutrophils, while the erythrocytes were negative. Cross-inhibition and sequential immunoprecipitation experiments demonstrated that these MoAbs recognised different epitopes either on a single molecule or on cross-reacting molecules. One antibody appeared to be raised against the monomorphic bovine beta-2-microglobulin, while the two other antibodies detected the heavy chain of polymorphic class I-like products. The authors propose that the BoLA class I polymorphism should be studied by determination of the fixation ratio of the monomorphic anti-beta 2M versus the polymorphic anticlass I antibodies amongst the animals." @default.
- W2000409284 created "2016-06-24" @default.
- W2000409284 creator A5018590824 @default.
- W2000409284 creator A5024983421 @default.
- W2000409284 creator A5028480429 @default.
- W2000409284 creator A5029980160 @default.
- W2000409284 creator A5030155143 @default.
- W2000409284 date "1986-11-01" @default.
- W2000409284 modified "2023-10-18" @default.
- W2000409284 title "Production and characterization of monoclonal antibodies raised against BoLA class I antigens" @default.
- W2000409284 cites W1505560697 @default.
- W2000409284 cites W1573709473 @default.
- W2000409284 cites W1592620039 @default.
- W2000409284 cites W1968101263 @default.
- W2000409284 cites W1969783034 @default.
- W2000409284 cites W1980097660 @default.
- W2000409284 cites W1988408076 @default.
- W2000409284 cites W2000538706 @default.
- W2000409284 cites W2011027287 @default.
- W2000409284 cites W2025342190 @default.
- W2000409284 cites W2026970642 @default.
- W2000409284 cites W2031905807 @default.
- W2000409284 cites W2058653058 @default.
- W2000409284 cites W2170924043 @default.
- W2000409284 doi "https://doi.org/10.1016/0165-2427(86)90074-7" @default.
- W2000409284 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3099453" @default.
- W2000409284 hasPublicationYear "1986" @default.
- W2000409284 type Work @default.
- W2000409284 sameAs 2000409284 @default.
- W2000409284 citedByCount "8" @default.
- W2000409284 crossrefType "journal-article" @default.
- W2000409284 hasAuthorship W2000409284A5018590824 @default.
- W2000409284 hasAuthorship W2000409284A5024983421 @default.
- W2000409284 hasAuthorship W2000409284A5028480429 @default.
- W2000409284 hasAuthorship W2000409284A5029980160 @default.
- W2000409284 hasAuthorship W2000409284A5030155143 @default.
- W2000409284 hasConcept C137061746 @default.
- W2000409284 hasConcept C147483822 @default.
- W2000409284 hasConcept C153911025 @default.
- W2000409284 hasConcept C159654299 @default.
- W2000409284 hasConcept C170627219 @default.
- W2000409284 hasConcept C176685330 @default.
- W2000409284 hasConcept C195616568 @default.
- W2000409284 hasConcept C202751555 @default.
- W2000409284 hasConcept C203014093 @default.
- W2000409284 hasConcept C207936829 @default.
- W2000409284 hasConcept C21957315 @default.
- W2000409284 hasConcept C30030713 @default.
- W2000409284 hasConcept C542903549 @default.
- W2000409284 hasConcept C55493867 @default.
- W2000409284 hasConcept C71829478 @default.
- W2000409284 hasConcept C86803240 @default.
- W2000409284 hasConceptScore W2000409284C137061746 @default.
- W2000409284 hasConceptScore W2000409284C147483822 @default.
- W2000409284 hasConceptScore W2000409284C153911025 @default.
- W2000409284 hasConceptScore W2000409284C159654299 @default.
- W2000409284 hasConceptScore W2000409284C170627219 @default.
- W2000409284 hasConceptScore W2000409284C176685330 @default.
- W2000409284 hasConceptScore W2000409284C195616568 @default.
- W2000409284 hasConceptScore W2000409284C202751555 @default.
- W2000409284 hasConceptScore W2000409284C203014093 @default.
- W2000409284 hasConceptScore W2000409284C207936829 @default.
- W2000409284 hasConceptScore W2000409284C21957315 @default.
- W2000409284 hasConceptScore W2000409284C30030713 @default.
- W2000409284 hasConceptScore W2000409284C542903549 @default.
- W2000409284 hasConceptScore W2000409284C55493867 @default.
- W2000409284 hasConceptScore W2000409284C71829478 @default.
- W2000409284 hasConceptScore W2000409284C86803240 @default.
- W2000409284 hasIssue "3" @default.
- W2000409284 hasLocation W20004092841 @default.
- W2000409284 hasLocation W20004092842 @default.
- W2000409284 hasOpenAccess W2000409284 @default.
- W2000409284 hasPrimaryLocation W20004092841 @default.
- W2000409284 hasRelatedWork W1411933917 @default.
- W2000409284 hasRelatedWork W1604248381 @default.
- W2000409284 hasRelatedWork W1964269825 @default.
- W2000409284 hasRelatedWork W199672269 @default.
- W2000409284 hasRelatedWork W2016785226 @default.
- W2000409284 hasRelatedWork W2030011033 @default.
- W2000409284 hasRelatedWork W2032580181 @default.
- W2000409284 hasRelatedWork W2064089409 @default.
- W2000409284 hasRelatedWork W208718216 @default.
- W2000409284 hasRelatedWork W2400620861 @default.
- W2000409284 hasVolume "13" @default.
- W2000409284 isParatext "false" @default.
- W2000409284 isRetracted "false" @default.
- W2000409284 magId "2000409284" @default.
- W2000409284 workType "article" @default.