Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000412326> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2000412326 abstract "Capsular polysaccharide, extracted from microorganism cultivations, is the principal antigen for elaboration of vaccine against the disease caused by Neisseria meningitidis serogroup C. The final protein content allowed in this vaccine is 1%. In order to find a relationship between nitrogen consumption and cell growth, including polysaccharide production, and cell nitrogen content, cultivations were carried out in an 80 liters bioreactor (total capacity), under the following conditions: Frantz medium; temperature of 35ºC; air flow of 5 L/min (0.125 vvm); agitation frequency of 120 rpm and vessel pressure of 6 psi (kLa = 0.07 min-1). Concentrations of biomass, total polysaccharide, cellular nitrogen, residual organic and inorganic nitrogen in the medium were measured during cultivation. From five cultivations carried out under the same conditions, a mean cell nitrogen percentage of 12.6% (w/w) in respect to the dry biomass was found. The inorganic nitrogen in the medium did not change significantly along the cultivation time, whereas the organic nitrogen consumption was linearly related to cell growth, with constant yield factors (average of 8.44). Polysaccharide production kinetics followed the cell growth kinetics until the beginning of the stationary growth phase. A supplemental polysaccharide production was observed until the end of cultivation, but without cell nitrogen absorption. Thus, the results indicate that polysaccharide is produced in two phases, being the first one biomass formation followed by non-associated to growth." @default.
- W2000412326 created "2016-06-24" @default.
- W2000412326 creator A5002979825 @default.
- W2000412326 creator A5003658747 @default.
- W2000412326 creator A5041557507 @default.
- W2000412326 creator A5053653723 @default.
- W2000412326 creator A5059174658 @default.
- W2000412326 creator A5059811780 @default.
- W2000412326 creator A5061896758 @default.
- W2000412326 creator A5069878139 @default.
- W2000412326 creator A5089366139 @default.
- W2000412326 date "2001-12-01" @default.
- W2000412326 modified "2023-10-10" @default.
- W2000412326 title "Nitrogen consumption during batch cultivation of Neisseria meningitidis (serogroup C) in Frantz medium" @default.
- W2000412326 cites W146682860 @default.
- W2000412326 cites W1533665484 @default.
- W2000412326 cites W1536299500 @default.
- W2000412326 cites W1818999139 @default.
- W2000412326 cites W1999773282 @default.
- W2000412326 cites W2019083734 @default.
- W2000412326 doi "https://doi.org/10.1590/s1517-83822001000400010" @default.
- W2000412326 hasPublicationYear "2001" @default.
- W2000412326 type Work @default.
- W2000412326 sameAs 2000412326 @default.
- W2000412326 citedByCount "8" @default.
- W2000412326 countsByYear W20004123262012 @default.
- W2000412326 countsByYear W20004123262013 @default.
- W2000412326 countsByYear W20004123262017 @default.
- W2000412326 crossrefType "journal-article" @default.
- W2000412326 hasAuthorship W2000412326A5002979825 @default.
- W2000412326 hasAuthorship W2000412326A5003658747 @default.
- W2000412326 hasAuthorship W2000412326A5041557507 @default.
- W2000412326 hasAuthorship W2000412326A5053653723 @default.
- W2000412326 hasAuthorship W2000412326A5059174658 @default.
- W2000412326 hasAuthorship W2000412326A5059811780 @default.
- W2000412326 hasAuthorship W2000412326A5061896758 @default.
- W2000412326 hasAuthorship W2000412326A5069878139 @default.
- W2000412326 hasAuthorship W2000412326A5089366139 @default.
- W2000412326 hasBestOaLocation W20004123261 @default.
- W2000412326 hasConcept C100817775 @default.
- W2000412326 hasConcept C115540264 @default.
- W2000412326 hasConcept C178790620 @default.
- W2000412326 hasConcept C185592680 @default.
- W2000412326 hasConcept C2778458888 @default.
- W2000412326 hasConcept C31903555 @default.
- W2000412326 hasConcept C523546767 @default.
- W2000412326 hasConcept C537208039 @default.
- W2000412326 hasConcept C54355233 @default.
- W2000412326 hasConcept C55493867 @default.
- W2000412326 hasConcept C6557445 @default.
- W2000412326 hasConcept C86803240 @default.
- W2000412326 hasConceptScore W2000412326C100817775 @default.
- W2000412326 hasConceptScore W2000412326C115540264 @default.
- W2000412326 hasConceptScore W2000412326C178790620 @default.
- W2000412326 hasConceptScore W2000412326C185592680 @default.
- W2000412326 hasConceptScore W2000412326C2778458888 @default.
- W2000412326 hasConceptScore W2000412326C31903555 @default.
- W2000412326 hasConceptScore W2000412326C523546767 @default.
- W2000412326 hasConceptScore W2000412326C537208039 @default.
- W2000412326 hasConceptScore W2000412326C54355233 @default.
- W2000412326 hasConceptScore W2000412326C55493867 @default.
- W2000412326 hasConceptScore W2000412326C6557445 @default.
- W2000412326 hasConceptScore W2000412326C86803240 @default.
- W2000412326 hasIssue "4" @default.
- W2000412326 hasLocation W20004123261 @default.
- W2000412326 hasLocation W20004123262 @default.
- W2000412326 hasLocation W20004123263 @default.
- W2000412326 hasOpenAccess W2000412326 @default.
- W2000412326 hasPrimaryLocation W20004123261 @default.
- W2000412326 hasRelatedWork W1844053279 @default.
- W2000412326 hasRelatedWork W1991382583 @default.
- W2000412326 hasRelatedWork W1994893698 @default.
- W2000412326 hasRelatedWork W2000412326 @default.
- W2000412326 hasRelatedWork W2037302825 @default.
- W2000412326 hasRelatedWork W2102700458 @default.
- W2000412326 hasRelatedWork W2159288820 @default.
- W2000412326 hasRelatedWork W2330258760 @default.
- W2000412326 hasRelatedWork W2801840297 @default.
- W2000412326 hasRelatedWork W2951722473 @default.
- W2000412326 hasVolume "32" @default.
- W2000412326 isParatext "false" @default.
- W2000412326 isRetracted "false" @default.
- W2000412326 magId "2000412326" @default.
- W2000412326 workType "article" @default.