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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000413379> ?p ?o ?g. }

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• W2000413379 abstract "Local perfusion of pGlu-Glu-Pro-NH2, an endogenous peptide structurally related to thyrotropine-releasing hormone (TRH), via in vivo microdialysis into the rat hippocampus did not change the basal level of extracellular acetylcholine. However, co-perfusion of pGlu-Glu-Pro-NH2 with TRH in equimolar concentrations yielded a significant attenuation of TRH-induced acetylcholine release. The results have supported the study's hypothesis that pGlu-Glu-Pro-NH2 opposes the cholinergic effect of TRH in the mammalian central nervous system. The enantiomer pGlu-d-Glu-Pro-NH2 affected neither basal extracellular nor TRH-induced increase of acetylcholine levels." @default.
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• W2000413379 date "2007-03-01" @default.
• W2000413379 modified "2023-10-17" @default.
• W2000413379 title "Evidence for interplay between thyrotropin-releasing hormone (TRH) and its structural analogue pGlu-Glu-Pro-NH2 ([Glu2]TRH) in the brain: An in vivo microdialysis study" @default.
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• W2000413379 doi "https://doi.org/10.1016/j.neulet.2006.12.039" @default.
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