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- W2000418701 abstract "The differentiation of naive T cells into distinct subsets of effector T cells is critical for effective immunity against a wide variety of infectious agents in the environment. Activation of innate immune responses by Candida species through pattern-recognition receptors directs the subsequent development of naive T cells into T(H)17 cells, which are essential for effective mucosal immunity against fungi. Thorough analyses of cohorts of patients with unusual susceptibility to chronic mucocutaneous candidiasis resulting from T(H)17 deficiency have confirmed the role of T(H)17 cells and T(H)17 cytokines in human host defense against Candida species and have provided valuable insights into the complex process of T(H)17 cell development." @default.
- W2000418701 created "2016-06-24" @default.
- W2000418701 creator A5076996270 @default.
- W2000418701 date "2012-06-01" @default.
- W2000418701 modified "2023-10-16" @default.
- W2000418701 title "TH17 deficiency in human disease" @default.
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- W2000418701 doi "https://doi.org/10.1016/j.jaci.2012.03.034" @default.
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