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- W2000420411 abstract "Neurotoxic injury of the caudate-putamen and lateral globus pallidus unilaterally initiated transneuronal degeneration of neurons in the ipsilateral substantia nigra reticulata (SNR). Quantification of SNR neurons using unbiased stereology demonstrated that neuron loss began 4 days after the initial striatal lesion, followed by significant loss (50%) at 6 days and a plateau at 8 days. Analysis at the light and ultrastructural levels revealed morphological changes consistent with a type of programmed cell death. These temporal and histological results refine an in vivo model in which to explore mechanisms of delayed neuronal degeneration." @default.
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- W2000420411 date "1998-06-01" @default.
- W2000420411 modified "2023-10-14" @default.
- W2000420411 title "Histological and temporal characteristics of nigral transneuronal degeneration after striatal injury" @default.
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- W2000420411 doi "https://doi.org/10.1016/s0006-8993(98)00247-9" @default.
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