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- W2000426406 abstract "An earlier report indicated that C57 bone marrow (BM) cells can be sensitized in vitro to transplantation antigens present on C3H macrophage monolayers. Such sensitized bone marrow cells can, after transfer to C57 recipients, cause accelerated rejection of C3H skin grafts. The present report indicates that thymus (T) cells, cultured with subthreshold numbers of bone marrow cells, stimulate the ability of such bone marrow cells to become sensitized in vitro. The stimulating effect is only demonstrable when thymus and bone marrow cells are both present during the in vitro sensitization process. C57 lymph node cells can also be sensitized in vitro to C3H transplantation antigens. Sensitized lymph node (LN) cells can transfer adoptive immunity to normal syngeneic, but not to X-irradiated, assay mice. In vitro sensitized bone marrow, on the other hand, can transfer adoptive immunity to irradiated assay mice." @default.
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- W2000426406 date "1972-03-01" @default.
- W2000426406 modified "2023-10-18" @default.
- W2000426406 title "IN VITRO SENSITIZATION TO TRANSPLANTATION ANTIGENS" @default.
- W2000426406 doi "https://doi.org/10.1097/00007890-197203000-00006" @default.
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