Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000429197> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2000429197 endingPage "266" @default.
- W2000429197 startingPage "259" @default.
- W2000429197 abstract "Rhabdoid tumor of kidney (RTK) is a rare, highly malignant childhood neoplasm of uncertain histogenesis. Several recent studies have described considerable histochemical heterogeneity among cases of RTK, with confusing combinations of epithelial, mesenchymal, myogenous, and neuroepithelial markers in some tumors. The present study characterizes the histology, ultrastructure, histochemistry, cytogenetics, and oncogene expression in a cell line derived from RTK. The surgical specimen, nude mouse xenograft, and cell cultures demonstrated characteristic intermediate filament whorls by electron microscopy and expressed vimentin (diffusely) and cytokeratin (focally, in hyaline cytoplasmic inclusions) without detectable desmin, Thy-1, or epithelial membrane antigen. S-100 protein was absent in the surgical specimen and heterotransplant, and was seen very weakly and focally in the cell cultures. Light microscopic features of cultures were unchanged by several compounds (tissue plasminogen activator, nerve growth factor, cyclic adenosine monophosphate) which induce differentiation of some other pediatric neoplasms. The grwoth factor requirements of RTK cultures indicate a cell with mesenchymal features. Insulin-like growth factor-2 mRNA was detected in the RTK and in three Wilms' tumors also studied. Unlike most Wilms' tumors, RTK expresses the c-myc rather than the N-myc oncogene." @default.
- W2000429197 created "2016-06-24" @default.
- W2000429197 creator A5041078594 @default.
- W2000429197 creator A5046194198 @default.
- W2000429197 creator A5057844881 @default.
- W2000429197 creator A5067230136 @default.
- W2000429197 creator A5081166985 @default.
- W2000429197 creator A5081207315 @default.
- W2000429197 creator A5084267082 @default.
- W2000429197 date "1991-03-01" @default.
- W2000429197 modified "2023-10-11" @default.
- W2000429197 title "Characterization of a cell line derived from rhabdoid tumor of kidney" @default.
- W2000429197 cites W1608177368 @default.
- W2000429197 cites W1965131913 @default.
- W2000429197 cites W1971557002 @default.
- W2000429197 cites W1999839467 @default.
- W2000429197 cites W2007768242 @default.
- W2000429197 cites W2028107173 @default.
- W2000429197 cites W2037994214 @default.
- W2000429197 cites W2052897755 @default.
- W2000429197 cites W2053126467 @default.
- W2000429197 cites W2077947721 @default.
- W2000429197 cites W2078261279 @default.
- W2000429197 cites W2082571806 @default.
- W2000429197 cites W2096428903 @default.
- W2000429197 cites W2113914075 @default.
- W2000429197 cites W2114668163 @default.
- W2000429197 cites W2164382839 @default.
- W2000429197 cites W2164972664 @default.
- W2000429197 cites W2178435844 @default.
- W2000429197 cites W2219623438 @default.
- W2000429197 cites W4292157265 @default.
- W2000429197 cites W4294216491 @default.
- W2000429197 cites W90890712 @default.
- W2000429197 doi "https://doi.org/10.1016/0046-8177(91)90160-q" @default.
- W2000429197 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1706306" @default.
- W2000429197 hasPublicationYear "1991" @default.
- W2000429197 type Work @default.
- W2000429197 sameAs 2000429197 @default.
- W2000429197 citedByCount "33" @default.
- W2000429197 countsByYear W20004291972012 @default.
- W2000429197 countsByYear W20004291972015 @default.
- W2000429197 crossrefType "journal-article" @default.
- W2000429197 hasAuthorship W2000429197A5041078594 @default.
- W2000429197 hasAuthorship W2000429197A5046194198 @default.
- W2000429197 hasAuthorship W2000429197A5057844881 @default.
- W2000429197 hasAuthorship W2000429197A5067230136 @default.
- W2000429197 hasAuthorship W2000429197A5081166985 @default.
- W2000429197 hasAuthorship W2000429197A5081207315 @default.
- W2000429197 hasAuthorship W2000429197A5084267082 @default.
- W2000429197 hasConcept C142724271 @default.
- W2000429197 hasConcept C147447768 @default.
- W2000429197 hasConcept C191548132 @default.
- W2000429197 hasConcept C198826908 @default.
- W2000429197 hasConcept C203014093 @default.
- W2000429197 hasConcept C204232928 @default.
- W2000429197 hasConcept C2775999222 @default.
- W2000429197 hasConcept C2778560582 @default.
- W2000429197 hasConcept C2779012181 @default.
- W2000429197 hasConcept C2779072444 @default.
- W2000429197 hasConcept C71924100 @default.
- W2000429197 hasConcept C86803240 @default.
- W2000429197 hasConcept C95444343 @default.
- W2000429197 hasConceptScore W2000429197C142724271 @default.
- W2000429197 hasConceptScore W2000429197C147447768 @default.
- W2000429197 hasConceptScore W2000429197C191548132 @default.
- W2000429197 hasConceptScore W2000429197C198826908 @default.
- W2000429197 hasConceptScore W2000429197C203014093 @default.
- W2000429197 hasConceptScore W2000429197C204232928 @default.
- W2000429197 hasConceptScore W2000429197C2775999222 @default.
- W2000429197 hasConceptScore W2000429197C2778560582 @default.
- W2000429197 hasConceptScore W2000429197C2779012181 @default.
- W2000429197 hasConceptScore W2000429197C2779072444 @default.
- W2000429197 hasConceptScore W2000429197C71924100 @default.
- W2000429197 hasConceptScore W2000429197C86803240 @default.
- W2000429197 hasConceptScore W2000429197C95444343 @default.
- W2000429197 hasIssue "3" @default.
- W2000429197 hasLocation W20004291971 @default.
- W2000429197 hasLocation W20004291972 @default.
- W2000429197 hasOpenAccess W2000429197 @default.
- W2000429197 hasPrimaryLocation W20004291971 @default.
- W2000429197 hasRelatedWork W12330244 @default.
- W2000429197 hasRelatedWork W1985366394 @default.
- W2000429197 hasRelatedWork W2028742232 @default.
- W2000429197 hasRelatedWork W2073415479 @default.
- W2000429197 hasRelatedWork W2073739140 @default.
- W2000429197 hasRelatedWork W2081416159 @default.
- W2000429197 hasRelatedWork W2157592070 @default.
- W2000429197 hasRelatedWork W2320624244 @default.
- W2000429197 hasRelatedWork W2412631431 @default.
- W2000429197 hasRelatedWork W2428021599 @default.
- W2000429197 hasVolume "22" @default.
- W2000429197 isParatext "false" @default.
- W2000429197 isRetracted "false" @default.
- W2000429197 magId "2000429197" @default.
- W2000429197 workType "article" @default.