Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000429216> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2000429216 endingPage "940" @default.
- W2000429216 startingPage "934" @default.
- W2000429216 abstract "Plasma extracts from patients with congenital adrenal hyperplasia were found to contain substances that competed with aldosterone for mineralocorticoid receptor-binding sites in a rat kidney cytosol system. In normal subjects and patients with other disorders, the mineralocorticoid receptor-binding activity in such extracts could be entirely accounted for by the sum of the contributions of the steroids known to bind to the mineralocorticoid receptor. The secretion of these binding substances in patients with the C-21 hydroxylation defect was ACTH dependent. While these substances could be either min-eralocorticoid agonists or antagonists, the latter is more likely. Production of mineralocorticoid antagonists would account for the compensatory hyperaldosteronism that occurs in the simple virilizing form, in which there is minimal impairment of aldosterone secretory reserve, and for the tendency to Addisonian crisis in patients with the salt-losing form, who have a more severe defect in aldosterone biosynthesis." @default.
- W2000429216 created "2016-06-24" @default.
- W2000429216 creator A5035311560 @default.
- W2000429216 creator A5068441189 @default.
- W2000429216 creator A5088463451 @default.
- W2000429216 date "1986-05-01" @default.
- W2000429216 modified "2023-09-25" @default.
- W2000429216 title "Evidence for the Secretion of an Antimineralocorticoid in Congenital Adrenal Hyperplasia*" @default.
- W2000429216 cites W1530187081 @default.
- W2000429216 cites W1559739749 @default.
- W2000429216 cites W1964994170 @default.
- W2000429216 cites W1969806517 @default.
- W2000429216 cites W1975574477 @default.
- W2000429216 cites W1976026761 @default.
- W2000429216 cites W1976842589 @default.
- W2000429216 cites W1986980085 @default.
- W2000429216 cites W1995754154 @default.
- W2000429216 cites W1996064462 @default.
- W2000429216 cites W1997061501 @default.
- W2000429216 cites W1999689946 @default.
- W2000429216 cites W2002367184 @default.
- W2000429216 cites W2018949273 @default.
- W2000429216 cites W2020447625 @default.
- W2000429216 cites W2027159638 @default.
- W2000429216 cites W2029633925 @default.
- W2000429216 cites W2031752348 @default.
- W2000429216 cites W2033261810 @default.
- W2000429216 cites W2037836361 @default.
- W2000429216 cites W2042180100 @default.
- W2000429216 cites W2044180167 @default.
- W2000429216 cites W2061560661 @default.
- W2000429216 cites W2086368273 @default.
- W2000429216 cites W2089924926 @default.
- W2000429216 cites W2092014119 @default.
- W2000429216 cites W2156614560 @default.
- W2000429216 doi "https://doi.org/10.1210/jcem-62-5-934" @default.
- W2000429216 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3007560" @default.
- W2000429216 hasPublicationYear "1986" @default.
- W2000429216 type Work @default.
- W2000429216 sameAs 2000429216 @default.
- W2000429216 citedByCount "26" @default.
- W2000429216 countsByYear W20004292162013 @default.
- W2000429216 countsByYear W20004292162014 @default.
- W2000429216 countsByYear W20004292162015 @default.
- W2000429216 countsByYear W20004292162016 @default.
- W2000429216 countsByYear W20004292162020 @default.
- W2000429216 countsByYear W20004292162023 @default.
- W2000429216 crossrefType "journal-article" @default.
- W2000429216 hasAuthorship W2000429216A5035311560 @default.
- W2000429216 hasAuthorship W2000429216A5068441189 @default.
- W2000429216 hasAuthorship W2000429216A5088463451 @default.
- W2000429216 hasConcept C126322002 @default.
- W2000429216 hasConcept C134018914 @default.
- W2000429216 hasConcept C170493617 @default.
- W2000429216 hasConcept C185592680 @default.
- W2000429216 hasConcept C189135053 @default.
- W2000429216 hasConcept C2776069600 @default.
- W2000429216 hasConcept C2776292634 @default.
- W2000429216 hasConcept C2777562237 @default.
- W2000429216 hasConcept C2777767042 @default.
- W2000429216 hasConcept C2778525890 @default.
- W2000429216 hasConcept C49039625 @default.
- W2000429216 hasConcept C71924100 @default.
- W2000429216 hasConcept C86803240 @default.
- W2000429216 hasConceptScore W2000429216C126322002 @default.
- W2000429216 hasConceptScore W2000429216C134018914 @default.
- W2000429216 hasConceptScore W2000429216C170493617 @default.
- W2000429216 hasConceptScore W2000429216C185592680 @default.
- W2000429216 hasConceptScore W2000429216C189135053 @default.
- W2000429216 hasConceptScore W2000429216C2776069600 @default.
- W2000429216 hasConceptScore W2000429216C2776292634 @default.
- W2000429216 hasConceptScore W2000429216C2777562237 @default.
- W2000429216 hasConceptScore W2000429216C2777767042 @default.
- W2000429216 hasConceptScore W2000429216C2778525890 @default.
- W2000429216 hasConceptScore W2000429216C49039625 @default.
- W2000429216 hasConceptScore W2000429216C71924100 @default.
- W2000429216 hasConceptScore W2000429216C86803240 @default.
- W2000429216 hasIssue "5" @default.
- W2000429216 hasLocation W20004292161 @default.
- W2000429216 hasLocation W20004292162 @default.
- W2000429216 hasOpenAccess W2000429216 @default.
- W2000429216 hasPrimaryLocation W20004292161 @default.
- W2000429216 hasRelatedWork W1981633019 @default.
- W2000429216 hasRelatedWork W2000429216 @default.
- W2000429216 hasRelatedWork W2012977668 @default.
- W2000429216 hasRelatedWork W2023418293 @default.
- W2000429216 hasRelatedWork W2037408526 @default.
- W2000429216 hasRelatedWork W2051808694 @default.
- W2000429216 hasRelatedWork W2105380188 @default.
- W2000429216 hasRelatedWork W2320425178 @default.
- W2000429216 hasRelatedWork W2530319271 @default.
- W2000429216 hasRelatedWork W32200126 @default.
- W2000429216 hasVolume "62" @default.
- W2000429216 isParatext "false" @default.
- W2000429216 isRetracted "false" @default.
- W2000429216 magId "2000429216" @default.
- W2000429216 workType "article" @default.