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- W2000431649 endingPage "621" @default.
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- W2000431649 abstract "Transforming growth factor-β (TGF-β) influences the development of myocardiopathy in Chagas disease through regulation of (i) parasite invasion of heart cells, (ii) an intracellular parasite cycle, (iii) inflammation and immune response, (iv) heart fibrosis and remodeling, and (v) gap junction modulation and heart conduction. In this review, we discuss the rationale for developing TGF-β signaling-interfering therapies as adjuvant approaches for the management of the cardiac alterations of Chagas disease-affected patients." @default.
- W2000431649 created "2016-06-24" @default.
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- W2000431649 date "2012-09-19" @default.
- W2000431649 modified "2023-10-14" @default.
- W2000431649 title "The TGF-β Pathway as an Emerging Target for Chagas Disease Therapy" @default.
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- W2000431649 doi "https://doi.org/10.1038/clpt.2012.102" @default.
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