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- W2000435166 abstract "Tissues from a two-month-old Japanese male infant with a typical angioblastoma of the skin on the right groin was examined by light and electron microscopy before and after soft X-ray therapy. Before therapy, nest-like proliferation of the tumor cells with frequent formation of vascular spaces was observed. Ultrastructurally, these tumor cells showed the morphological characteristics of vascular endothelial cells in their size, shape and usual organelles. These cells usually had an abundance of peculiar dense granules with a limiting membrane. Fibrin deposits and thrombosis with aggregations of platelets were observed in the lumina in situ. After soft X-ray therapy with a total dose of 3,600 rads, disappearance of most of the tumor cell-nests and prominent dilatation of the residual vessels were observed. Ultrastructurally, numbers of the vessels showed more or less degenerative and destructive changes. Vessels with ruptured endothelial cell linings, extravasated red cells, and hemosiderin deposits were also frequently observed. From these findings, it is concluded that angioblastoma of the skin should be considered as one of the benign hemangiomas of the skin, and that degenerative changes in the endothelial cells induced by irradiation are almost identical to those in other conditions." @default.
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- W2000435166 date "1981-06-01" @default.
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- W2000435166 title "ULTRASTRUCTURE OF SO-CALLED ANGIOBLASTOMA OF THE SKIN BEFORE AND AFTER SOFT X-RAY THERAPY" @default.
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- W2000435166 doi "https://doi.org/10.1111/j.1346-8138.1981.tb02540.x" @default.
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