Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000436622> ?p ?o ?g. }
- W2000436622 endingPage "2266" @default.
- W2000436622 startingPage "2258" @default.
- W2000436622 abstract "In this study the membrane orientation of a tryptophan-flanked model peptide, WALP23, was determined by using peptides that were labeled at different positions along the sequence with the environmentally sensitive fluorescent label BADAN. The fluorescence properties, reflecting the local polarity, were used to determine the tilt and rotation angles of the peptide based on an ideal alpha-helix model. For WALP23 inserted in dioleoylphosphatidylcholine (DOPC), an estimated tilt angle of the helix with respect to the bilayer normal of 24 degrees +/- 5 degrees was obtained. When the peptides were inserted into bilayers with different acyl chain lengths or containing different concentrations of cholesterol, small changes in tilt angle were observed as response to hydrophobic mismatch, whereas the rotation angle appeared to be independent of lipid composition. In all cases, the tilt angles were significantly larger than those previously determined from (2)H NMR experiments, supporting recent suggestions that the relatively long timescale of (2)H NMR measurements may result in an underestimation of tilt angles due to partial motional averaging. It is concluded that although the fluorescence technique has a rather low resolution and limited accuracy, it can be used to resolve the discrepancies observed between previous (2)H NMR experiments and molecular-dynamics simulations." @default.
- W2000436622 created "2016-06-24" @default.
- W2000436622 creator A5020444863 @default.
- W2000436622 creator A5034888541 @default.
- W2000436622 creator A5052050368 @default.
- W2000436622 creator A5054562365 @default.
- W2000436622 creator A5055415779 @default.
- W2000436622 creator A5081776749 @default.
- W2000436622 creator A5087844186 @default.
- W2000436622 date "2009-10-01" @default.
- W2000436622 modified "2023-09-26" @default.
- W2000436622 title "Tilt and Rotation Angles of a Transmembrane Model Peptide as Studied by Fluorescence Spectroscopy" @default.
- W2000436622 cites W1968299564 @default.
- W2000436622 cites W1984180966 @default.
- W2000436622 cites W1992909182 @default.
- W2000436622 cites W1994673901 @default.
- W2000436622 cites W1996795941 @default.
- W2000436622 cites W1999420570 @default.
- W2000436622 cites W2000729091 @default.
- W2000436622 cites W2005784403 @default.
- W2000436622 cites W2008708240 @default.
- W2000436622 cites W2011577346 @default.
- W2000436622 cites W2014239966 @default.
- W2000436622 cites W2016989448 @default.
- W2000436622 cites W2028665842 @default.
- W2000436622 cites W2034133104 @default.
- W2000436622 cites W2035035273 @default.
- W2000436622 cites W2052002053 @default.
- W2000436622 cites W2058496393 @default.
- W2000436622 cites W2059625238 @default.
- W2000436622 cites W2065216794 @default.
- W2000436622 cites W2074114336 @default.
- W2000436622 cites W2074970514 @default.
- W2000436622 cites W2075348086 @default.
- W2000436622 cites W2075836002 @default.
- W2000436622 cites W2077817323 @default.
- W2000436622 cites W2080740960 @default.
- W2000436622 cites W2096911475 @default.
- W2000436622 cites W2097364162 @default.
- W2000436622 cites W2097498028 @default.
- W2000436622 cites W2110070108 @default.
- W2000436622 cites W2113534084 @default.
- W2000436622 cites W2115252051 @default.
- W2000436622 cites W2125802349 @default.
- W2000436622 cites W2128628166 @default.
- W2000436622 cites W2148724380 @default.
- W2000436622 cites W4248208651 @default.
- W2000436622 doi "https://doi.org/10.1016/j.bpj.2009.07.042" @default.
- W2000436622 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2764067" @default.
- W2000436622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19843458" @default.
- W2000436622 hasPublicationYear "2009" @default.
- W2000436622 type Work @default.
- W2000436622 sameAs 2000436622 @default.
- W2000436622 citedByCount "45" @default.
- W2000436622 countsByYear W20004366222012 @default.
- W2000436622 countsByYear W20004366222013 @default.
- W2000436622 countsByYear W20004366222014 @default.
- W2000436622 countsByYear W20004366222015 @default.
- W2000436622 countsByYear W20004366222016 @default.
- W2000436622 countsByYear W20004366222017 @default.
- W2000436622 countsByYear W20004366222018 @default.
- W2000436622 countsByYear W20004366222020 @default.
- W2000436622 countsByYear W20004366222021 @default.
- W2000436622 countsByYear W20004366222022 @default.
- W2000436622 countsByYear W20004366222023 @default.
- W2000436622 crossrefType "journal-article" @default.
- W2000436622 hasAuthorship W2000436622A5020444863 @default.
- W2000436622 hasAuthorship W2000436622A5034888541 @default.
- W2000436622 hasAuthorship W2000436622A5052050368 @default.
- W2000436622 hasAuthorship W2000436622A5054562365 @default.
- W2000436622 hasAuthorship W2000436622A5055415779 @default.
- W2000436622 hasAuthorship W2000436622A5081776749 @default.
- W2000436622 hasAuthorship W2000436622A5087844186 @default.
- W2000436622 hasBestOaLocation W20004366221 @default.
- W2000436622 hasConcept C120665830 @default.
- W2000436622 hasConcept C121332964 @default.
- W2000436622 hasConcept C12554922 @default.
- W2000436622 hasConcept C138268822 @default.
- W2000436622 hasConcept C154945302 @default.
- W2000436622 hasConcept C158711907 @default.
- W2000436622 hasConcept C185592680 @default.
- W2000436622 hasConcept C18903297 @default.
- W2000436622 hasConcept C192157962 @default.
- W2000436622 hasConcept C2524010 @default.
- W2000436622 hasConcept C2778530040 @default.
- W2000436622 hasConcept C2779281246 @default.
- W2000436622 hasConcept C2779844322 @default.
- W2000436622 hasConcept C2779965526 @default.
- W2000436622 hasConcept C33923547 @default.
- W2000436622 hasConcept C39944091 @default.
- W2000436622 hasConcept C41008148 @default.
- W2000436622 hasConcept C41625074 @default.
- W2000436622 hasConcept C55493867 @default.
- W2000436622 hasConcept C74050887 @default.
- W2000436622 hasConcept C8010536 @default.
- W2000436622 hasConcept C86803240 @default.
- W2000436622 hasConcept C91881484 @default.
- W2000436622 hasConceptScore W2000436622C120665830 @default.