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• W2000436669 abstract "Hooded Gunn rats which have low-activity of 4-nitrophenol uridine diphosphate-glucuronosyltransferase (GT) and defect in bilirubin GT were crossed with albino LA Wistar rats with a defect in androsterone GT. From F2 and F3 progeny were selected Gunn-LA Wistar rats which have defective bilirubin and androsterone GTs and low-active 4-nitrophenol GT. These rats had either hooded or albino coat color. In order to establish a uniform genetic background, albino male Gunn-LA Wistar rats were crossed with heterozygous albino female Gunn-LA Wistar rats in terms of bilirubin GT. The offsprings were all albino and were classified to Gunn-LA Wistar rats and heterozygous Gunn-LA Wistar rats by assaying their hepatic GT activities or by the appearance of jaundice. The linkage relationships between GT and coat color genes are discussed." @default.
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• W2000436669 date "1989-01-01" @default.
• W2000436669 modified "2023-09-25" @default.
• W2000436669 title "A new mutant strain of Gunn-LA Wistar rats with genetic deficiencies in bilirubin and androsterone uridine diphosphate-glucuronosyltransferases." @default.
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• W2000436669 doi "https://doi.org/10.1248/bpb1978.12.305" @default.
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