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• W2000436908 abstract "13 patients suffering from local atrophy or loss of the alveolar process of the jaws were treated by subperiosteal implantation of allogenous, decalcified, sterilized dentin with the purpose of augmentation of the alveolar process. All patients, including 9 donors of dentin were ABO-, Rh-, and HLA tissue typed. Antidonor cell-mediated immunity (CMI) and humoral-mediated immunity (HMI) of the patients were monitored during the first 6 postoperative months. The CMI and HMI were assessed by means of the leucocyte migration test (LMT) and the complement dependent microlymphocytotoxicity test (CDQ with donor leucocytes as antigen and target cells, respectively. Compared to 66 normal non-transplanted controls, the leucocyte migration inhibition against desintegrated donor leucocytes as antigen was significantly increased for 2 of the recipients during the control period. 1 of these recipients showed a simultaneous HMI reaction 6 weeks after implantation. The remaining CMI and HMI values of the recipients were within normal range. These results were not correlated with the histocompatibility match grades of the donor recipient pairs. The present investigation supports the suggestion that implantation of allogenous, decalcified and sterilized dentin occasionally is capable of eliciting a measureable alloimmune response." @default.
• W2000436908 created "2016-06-24" @default.
• W2000436908 creator A5054685637 @default.
• W2000436908 date "1983-04-01" @default.
• W2000436908 modified "2023-10-12" @default.
• W2000436908 title "Cell-mediated and humoral alloimmunreactions after subperiostal implantation of allogenic demineralized dentin in humans" @default.
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• W2000436908 doi "https://doi.org/10.1016/s0300-9785(83)80004-0" @default.
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