FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000436995> ?p ?o ?g. }

• W2000436995 abstract "The possibility that Ca2+ store depletion can stimulate contraction of the rat portal vein was investigated in functional experiments. Ca2+ stores were depleted with phenylephrine or cyclopiazonic acid in the absence of extracellular Ca2+ and then washed out for 30 min. Upon re-addition of extracellular Ca2+, a tonic contraction was produced, showing the stimulus for contraction was Ca2+ store depletion. The contractions were abolished by niflumic acid and nifedipine however, indicating they were dependent on depolarization resulting from opening of Ca2+-activated Cl- channels and Ca2+ influx through voltage-gated channels. Cumulative additions of phenylephrine below 3x10(-6) M did not produce tonic contractions but did in high K+ Krebs solution, where levcromakalim had no effect. This showed the tonic contractions were initially prevented by K+ channel opening. Increased Ca2+ entry through voltage-gated channels may therefore stimulate Ca2+-activated Cl- channels. Ca2+ store depletion could stimulate this by opening store-operated non-selective cation channels, resulting in depolarization." @default.
• W2000436995 created "2016-06-24" @default.
• W2000436995 creator A5058994056 @default.
• W2000436995 date "2005-03-01" @default.
• W2000436995 modified "2023-09-27" @default.
• W2000436995 title "Depletion of Ca2+ from intracellular stores of the rat portal vein stimulates a tonic contraction" @default.
• W2000436995 cites W1546706272 @default.
• W2000436995 cites W1571332834 @default.
• W2000436995 cites W1591492241 @default.
• W2000436995 cites W1965646654 @default.
• W2000436995 cites W1975479233 @default.
• W2000436995 cites W1988458046 @default.
• W2000436995 cites W1989323461 @default.
• W2000436995 cites W1996088859 @default.
• W2000436995 cites W1998637138 @default.
• W2000436995 cites W2000923181 @default.
• W2000436995 cites W2001558241 @default.
• W2000436995 cites W2006088971 @default.
• W2000436995 cites W2012207925 @default.
• W2000436995 cites W2014856276 @default.
• W2000436995 cites W2015480034 @default.
• W2000436995 cites W2021487722 @default.
• W2000436995 cites W2024753218 @default.
• W2000436995 cites W2031943544 @default.
• W2000436995 cites W2040773535 @default.
• W2000436995 cites W2041690080 @default.
• W2000436995 cites W2053478909 @default.
• W2000436995 cites W2070832223 @default.
• W2000436995 cites W2075473225 @default.
• W2000436995 cites W2076921705 @default.
• W2000436995 cites W2087408563 @default.
• W2000436995 cites W2117312810 @default.
• W2000436995 cites W2126058709 @default.
• W2000436995 cites W2146707932 @default.
• W2000436995 cites W2148806848 @default.
• W2000436995 cites W2152481866 @default.
• W2000436995 cites W4255140376 @default.
• W2000436995 doi "https://doi.org/10.1016/j.ejphar.2005.01.021" @default.
• W2000436995 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15740729" @default.
• W2000436995 hasPublicationYear "2005" @default.
• W2000436995 type Work @default.
• W2000436995 sameAs 2000436995 @default.
• W2000436995 citedByCount "5" @default.
• W2000436995 countsByYear W20004369952012 @default.
• W2000436995 countsByYear W20004369952013 @default.
• W2000436995 countsByYear W20004369952021 @default.
• W2000436995 crossrefType "journal-article" @default.
• W2000436995 hasAuthorship W2000436995A5058994056 @default.
• W2000436995 hasConcept C12554922 @default.
• W2000436995 hasConcept C126322002 @default.
• W2000436995 hasConcept C127573956 @default.
• W2000436995 hasConcept C131453863 @default.
• W2000436995 hasConcept C153461711 @default.
• W2000436995 hasConcept C163415756 @default.
• W2000436995 hasConcept C178790620 @default.
• W2000436995 hasConcept C185592680 @default.
• W2000436995 hasConcept C2776050358 @default.
• W2000436995 hasConcept C2777952589 @default.
• W2000436995 hasConcept C2779066535 @default.
• W2000436995 hasConcept C2779700409 @default.
• W2000436995 hasConcept C2779996123 @default.
• W2000436995 hasConcept C28406088 @default.
• W2000436995 hasConcept C4141045 @default.
• W2000436995 hasConcept C519063684 @default.
• W2000436995 hasConcept C55493867 @default.
• W2000436995 hasConcept C66974803 @default.
• W2000436995 hasConcept C71240020 @default.
• W2000436995 hasConcept C71924100 @default.
• W2000436995 hasConcept C79879829 @default.
• W2000436995 hasConcept C84393581 @default.
• W2000436995 hasConcept C86803240 @default.
• W2000436995 hasConceptScore W2000436995C12554922 @default.
• W2000436995 hasConceptScore W2000436995C126322002 @default.
• W2000436995 hasConceptScore W2000436995C127573956 @default.
• W2000436995 hasConceptScore W2000436995C131453863 @default.
• W2000436995 hasConceptScore W2000436995C153461711 @default.
• W2000436995 hasConceptScore W2000436995C163415756 @default.
• W2000436995 hasConceptScore W2000436995C178790620 @default.
• W2000436995 hasConceptScore W2000436995C185592680 @default.
• W2000436995 hasConceptScore W2000436995C2776050358 @default.
• W2000436995 hasConceptScore W2000436995C2777952589 @default.
• W2000436995 hasConceptScore W2000436995C2779066535 @default.
• W2000436995 hasConceptScore W2000436995C2779700409 @default.
• W2000436995 hasConceptScore W2000436995C2779996123 @default.
• W2000436995 hasConceptScore W2000436995C28406088 @default.
• W2000436995 hasConceptScore W2000436995C4141045 @default.
• W2000436995 hasConceptScore W2000436995C519063684 @default.
• W2000436995 hasConceptScore W2000436995C55493867 @default.
• W2000436995 hasConceptScore W2000436995C66974803 @default.
• W2000436995 hasConceptScore W2000436995C71240020 @default.
• W2000436995 hasConceptScore W2000436995C71924100 @default.
• W2000436995 hasConceptScore W2000436995C79879829 @default.
• W2000436995 hasConceptScore W2000436995C84393581 @default.
• W2000436995 hasConceptScore W2000436995C86803240 @default.
• W2000436995 hasLocation W20004369951 @default.
• W2000436995 hasLocation W20004369952 @default.
• W2000436995 hasOpenAccess W2000436995 @default.
• W2000436995 hasPrimaryLocation W20004369951 @default.
• W2000436995 hasRelatedWork W1835419280 @default.
• W2000436995 hasRelatedWork W2000436995 @default.

• next