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- W2000442860 abstract "Serotonin facilitates fear learning in animals. We therefore predicted that individual differences in the capacity to regulate serotonergic transmission in the human neural fear circuit would be inversely related to fear conditioning. The capacity to regulate serotonergic transmission was indexed by serotonin transporter availability measured with [11C]-DASB positron emission tomography. Results indicate that lower serotonin transporter availability in the amygdala, insula and dorsal anterior cingulate cortex predicts enhanced conditioned autonomic fear responses. Our finding supports serotonergic modulation of fear conditioning in humans and may aid in understanding susceptibility for developing anxiety conditions such as post-traumatic stress disorder." @default.
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- W2000442860 date "2015-12-01" @default.
- W2000442860 modified "2023-10-16" @default.
- W2000442860 title "Human serotonin transporter availability predicts fear conditioning" @default.
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- W2000442860 doi "https://doi.org/10.1016/j.ijpsycho.2014.12.002" @default.
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