Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000448043> ?p ?o ?g. }
- W2000448043 endingPage "242" @default.
- W2000448043 startingPage "237" @default.
- W2000448043 abstract "Children of women who consume high amounts of alcohol during their pregnancies vary greatly in physical and behavioral outcomes. Although many factors, such as dose and timing of exposure, undoubtedly contribute to this variation, one important determinant may be genetic differences in the response to alcohol. The present study examined activity levels in high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats following neonatal alcohol exposure. These lines were selectively bred for extremes in ethanol-induced “sleep times.” The HAS and LAS offspring were exposed to alcohol via an artificial rearing procedure using the “pup-in-the-cup” technique. Rat pups were exposed to ethanol (6 g/kg/day) from postnatal day (PD) 4 through 7 and faded to a dose of 3 g/kg/day on PD 8 and 9. An artificially reared gastrostomy control group (GC) and a normally reared suckle control group (SC) were also included. Activity level was measured on PD 18 through PD 21 for 30 min daily in automated activity monitors. Neonatal ethanol exposure produced overactivity in HAS rats, relative to their controls, but the same ethanol treatment had no effect on the LAS rats. Importantly, there were no differences in blood alcohol concentrations (around 420 mg/dl) between the two lines during the treatment period. These data suggest that genetic differences in response to alcohol may be a predictor for some of the behavioral teratogenic effects of alcohol." @default.
- W2000448043 created "2016-06-24" @default.
- W2000448043 creator A5046805135 @default.
- W2000448043 creator A5067266829 @default.
- W2000448043 creator A5068687800 @default.
- W2000448043 creator A5079016745 @default.
- W2000448043 date "1998-10-01" @default.
- W2000448043 modified "2023-09-26" @default.
- W2000448043 title "Neonatal Alcohol Exposure Produces Hyperactivity in High-Alcohol-Sensitive But Not in Low-Alcohol-Sensitive Rats" @default.
- W2000448043 cites W1746739420 @default.
- W2000448043 cites W1963720808 @default.
- W2000448043 cites W1965199787 @default.
- W2000448043 cites W1977448828 @default.
- W2000448043 cites W1977701685 @default.
- W2000448043 cites W1987871375 @default.
- W2000448043 cites W1990736154 @default.
- W2000448043 cites W1992958853 @default.
- W2000448043 cites W1997506099 @default.
- W2000448043 cites W1997758852 @default.
- W2000448043 cites W2008646949 @default.
- W2000448043 cites W2009028062 @default.
- W2000448043 cites W2024288519 @default.
- W2000448043 cites W2026952527 @default.
- W2000448043 cites W2029115611 @default.
- W2000448043 cites W2037187944 @default.
- W2000448043 cites W2037646365 @default.
- W2000448043 cites W2043110199 @default.
- W2000448043 cites W2043242159 @default.
- W2000448043 cites W2051362675 @default.
- W2000448043 cites W2051969865 @default.
- W2000448043 cites W2052603928 @default.
- W2000448043 cites W2062648512 @default.
- W2000448043 cites W2076258150 @default.
- W2000448043 cites W2077821552 @default.
- W2000448043 cites W2080131125 @default.
- W2000448043 cites W2080527942 @default.
- W2000448043 cites W2081336349 @default.
- W2000448043 cites W2083570114 @default.
- W2000448043 cites W2085469734 @default.
- W2000448043 cites W2085707848 @default.
- W2000448043 cites W2089090965 @default.
- W2000448043 cites W2112230314 @default.
- W2000448043 cites W2123610014 @default.
- W2000448043 cites W2143437800 @default.
- W2000448043 cites W2154885337 @default.
- W2000448043 cites W74979492 @default.
- W2000448043 doi "https://doi.org/10.1016/s0741-8329(98)00008-1" @default.
- W2000448043 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9744855" @default.
- W2000448043 hasPublicationYear "1998" @default.
- W2000448043 type Work @default.
- W2000448043 sameAs 2000448043 @default.
- W2000448043 citedByCount "25" @default.
- W2000448043 countsByYear W20004480432012 @default.
- W2000448043 countsByYear W20004480432013 @default.
- W2000448043 countsByYear W20004480432019 @default.
- W2000448043 countsByYear W20004480432023 @default.
- W2000448043 crossrefType "journal-article" @default.
- W2000448043 hasAuthorship W2000448043A5046805135 @default.
- W2000448043 hasAuthorship W2000448043A5067266829 @default.
- W2000448043 hasAuthorship W2000448043A5068687800 @default.
- W2000448043 hasAuthorship W2000448043A5079016745 @default.
- W2000448043 hasConcept C112672928 @default.
- W2000448043 hasConcept C126322002 @default.
- W2000448043 hasConcept C134018914 @default.
- W2000448043 hasConcept C2777601104 @default.
- W2000448043 hasConcept C2779234561 @default.
- W2000448043 hasConcept C2780161600 @default.
- W2000448043 hasConcept C2781066024 @default.
- W2000448043 hasConcept C2909481879 @default.
- W2000448043 hasConcept C3018430727 @default.
- W2000448043 hasConcept C42407357 @default.
- W2000448043 hasConcept C54355233 @default.
- W2000448043 hasConcept C55493867 @default.
- W2000448043 hasConcept C71924100 @default.
- W2000448043 hasConcept C86803240 @default.
- W2000448043 hasConceptScore W2000448043C112672928 @default.
- W2000448043 hasConceptScore W2000448043C126322002 @default.
- W2000448043 hasConceptScore W2000448043C134018914 @default.
- W2000448043 hasConceptScore W2000448043C2777601104 @default.
- W2000448043 hasConceptScore W2000448043C2779234561 @default.
- W2000448043 hasConceptScore W2000448043C2780161600 @default.
- W2000448043 hasConceptScore W2000448043C2781066024 @default.
- W2000448043 hasConceptScore W2000448043C2909481879 @default.
- W2000448043 hasConceptScore W2000448043C3018430727 @default.
- W2000448043 hasConceptScore W2000448043C42407357 @default.
- W2000448043 hasConceptScore W2000448043C54355233 @default.
- W2000448043 hasConceptScore W2000448043C55493867 @default.
- W2000448043 hasConceptScore W2000448043C71924100 @default.
- W2000448043 hasConceptScore W2000448043C86803240 @default.
- W2000448043 hasIssue "3" @default.
- W2000448043 hasLocation W20004480431 @default.
- W2000448043 hasLocation W20004480432 @default.
- W2000448043 hasOpenAccess W2000448043 @default.
- W2000448043 hasPrimaryLocation W20004480431 @default.
- W2000448043 hasRelatedWork W1533294548 @default.
- W2000448043 hasRelatedWork W1591616590 @default.
- W2000448043 hasRelatedWork W1987062717 @default.
- W2000448043 hasRelatedWork W2000448043 @default.