Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000452643> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2000452643 endingPage "2152" @default.
- W2000452643 startingPage "2152" @default.
- W2000452643 abstract "David B. Rein, PhD; John S. Wittenborn, BS; Xinzhi Zhang, MD, PhD; Amanda A. Honeycutt, PhD; Sarah B. Lesesne, BS; Jinan Saaddine, MD, MPH; for the Vision Health Cost-Effectiveness Study GroupObjective: To forecast age-related macular degeneration (AMD) and its consequences in the United States through the year 2050 with different treatment scenarios.Methods: We simulated cases of early AMD, choroidal neovascularization (CNV), geographic atrophy (GA), and AMD-attributable visual impairment and blindness with 5 universal treatment scenarios: (1) no treatment; (2) focal laser and photodynamic therapy (PDT) for CNV; (3) vitamin prophylaxis at early-AMD incidence with focal laser/PDT for CNV; (4) no vitamin prophylaxis followed by focal laser treatment for extra and juxtafoveal CNV and anti–vascular endothelial growth factor treatment; and (5) vitamin prophylaxis at early-AMD incidence followed by CNV treatment, as in scenario 4.Results: Cases of early AMD increased from 9.1 million in 2010 to 17.8 million in 2050 across all scenarios. In non–vitamin-receiving scenarios, cases of CNV and GA increased from 1.7 million in 2010 to 3.8 million in 2050 (25% lower in vitamin-receiving scenarios). Cases of visual impairment and blindness increased from 620 000 in 2010 to 1.6 million in 2050 when given no treatment and were 2.4%, 22.0%, 16.9%, and 34.5% lower in scenarios 2, 3, 4, and 5, respectively.Conclusion: Prevalence of AMD will increase substantially by 2050, but the use of new therapies can mitigate its effects." @default.
- W2000452643 created "2016-06-24" @default.
- W2000452643 creator A5026764667 @default.
- W2000452643 creator A5061631272 @default.
- W2000452643 date "2009-05-27" @default.
- W2000452643 modified "2023-09-26" @default.
- W2000452643 title "Forecasting Age-Related Macular Degeneration Through 2050" @default.
- W2000452643 cites W1522272765 @default.
- W2000452643 cites W1565600091 @default.
- W2000452643 cites W1988245456 @default.
- W2000452643 cites W200886222 @default.
- W2000452643 cites W2030457549 @default.
- W2000452643 cites W2039538435 @default.
- W2000452643 cites W2048601306 @default.
- W2000452643 cites W2113784410 @default.
- W2000452643 cites W2124415048 @default.
- W2000452643 cites W2141960190 @default.
- W2000452643 cites W2144523453 @default.
- W2000452643 cites W2598520882 @default.
- W2000452643 doi "https://doi.org/10.1001/jama.2009.729" @default.
- W2000452643 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19475785" @default.
- W2000452643 hasPublicationYear "2009" @default.
- W2000452643 type Work @default.
- W2000452643 sameAs 2000452643 @default.
- W2000452643 citedByCount "22" @default.
- W2000452643 countsByYear W20004526432012 @default.
- W2000452643 countsByYear W20004526432013 @default.
- W2000452643 countsByYear W20004526432014 @default.
- W2000452643 countsByYear W20004526432017 @default.
- W2000452643 countsByYear W20004526432019 @default.
- W2000452643 countsByYear W20004526432020 @default.
- W2000452643 countsByYear W20004526432021 @default.
- W2000452643 countsByYear W20004526432022 @default.
- W2000452643 crossrefType "journal-article" @default.
- W2000452643 hasAuthorship W2000452643A5026764667 @default.
- W2000452643 hasAuthorship W2000452643A5061631272 @default.
- W2000452643 hasConcept C118487528 @default.
- W2000452643 hasConcept C119767625 @default.
- W2000452643 hasConcept C2776403814 @default.
- W2000452643 hasConcept C2779354088 @default.
- W2000452643 hasConcept C71924100 @default.
- W2000452643 hasConceptScore W2000452643C118487528 @default.
- W2000452643 hasConceptScore W2000452643C119767625 @default.
- W2000452643 hasConceptScore W2000452643C2776403814 @default.
- W2000452643 hasConceptScore W2000452643C2779354088 @default.
- W2000452643 hasConceptScore W2000452643C71924100 @default.
- W2000452643 hasIssue "20" @default.
- W2000452643 hasLocation W20004526431 @default.
- W2000452643 hasLocation W20004526432 @default.
- W2000452643 hasOpenAccess W2000452643 @default.
- W2000452643 hasPrimaryLocation W20004526431 @default.
- W2000452643 hasRelatedWork W1021594047 @default.
- W2000452643 hasRelatedWork W1145802917 @default.
- W2000452643 hasRelatedWork W1425672236 @default.
- W2000452643 hasRelatedWork W1645438978 @default.
- W2000452643 hasRelatedWork W2027517098 @default.
- W2000452643 hasRelatedWork W2074855306 @default.
- W2000452643 hasRelatedWork W3184393438 @default.
- W2000452643 hasRelatedWork W4206927669 @default.
- W2000452643 hasRelatedWork W766991852 @default.
- W2000452643 hasRelatedWork W935857850 @default.
- W2000452643 hasVolume "301" @default.
- W2000452643 isParatext "false" @default.
- W2000452643 isRetracted "false" @default.
- W2000452643 magId "2000452643" @default.
- W2000452643 workType "article" @default.