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• W2000453346 abstract "The alveolar-capillary O2 exchange was studied in 13 anesthetized dogs, average weight 25 kg, breathing 11 % O2 in N2, while their O2 consumption was increased stepwise by intravenous administration of 2:4-dinitrophenol. The apparent O2 diffusing capacity, DO2, calculated from ideal alveolar, arterial and mixed venous PO2, averaged 22 ml/min-mm Hg in control conditions, and reached 52 ml/min- mm Hg as the O2 uptake was increased 7.7 times above the control value. Comparison with the behavior of the single breath DCO and consideration of the disturbing effects of inhomogeneities in the lungs upon measurements of DO2 and DCO make it probable that the increase of DO2 was spurious, produced by functional inhomogeneities of the lungs, and that the true DO2, value was about 70 ml/min- mm Hg at all levels of O2 uptake." @default.
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• W2000453346 date "1969-02-01" @default.
• W2000453346 modified "2023-10-18" @default.
• W2000453346 title "Pulmonary diffusing capacity at basal and increased O2 uptake levels in anesthetized dogs" @default.
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• W2000453346 doi "https://doi.org/10.1016/0034-5687(69)90060-7" @default.
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