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- W2000453411 abstract "Novel glycosidic gossypol analogs, 7,7′-gossypol diglucoside tetraacetate GS1, 6,7′-gossypol diglucoside tetraacetate GS2, 7,7′-gossypol diglycoside GS1′, 6,7′-gossypol diglycoside GS2′ were obtained by the ultrasound-assisted reaction of the potassium salt of gossypol with 2,3,4,6-tetra-O-acetyl-α-d-glucopyranosyl bromide under PTC conditions and were fully characterized by 1D NMR (1H NMR, 13C NMR, DEPT, 1D NOE), 2D NMR (HMBC, HMQC), FTIR, HRMS and HPLC. The anticancer activities, cytotoxic effects as well as anti-trypanosomal activities of these novel glycosidic gossypols were explored and suggest that gossypol glycosides could be used to develop new candidates for anticancer drugs and anti-trypanosomal agents." @default.
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- W2000453411 date "2011-10-01" @default.
- W2000453411 modified "2023-10-16" @default.
- W2000453411 title "Novel O-glycosidic gossypol isomers and their bioactivities" @default.
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- W2000453411 doi "https://doi.org/10.1016/j.carres.2011.06.031" @default.
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