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- W2000454017 abstract "Sulfated beta-(1-->4)-galacto-oligosaccharides were prepared from an arabino-galacto-rhamno-galacturonan from Lupinus polyphyllus Lindl. by successive partial hydrolysis and SO3-pyridine sulfation in DMF. The resulting oligosaccharide polysulfates were analyzed by analytical GPC and the sulfate content was determined by ion chromatography. DP 5 and higher showed a pronounced antiangiogenic effect with scores of 0.9-1.2 for DP 7-9 using the CAM-assay. An interaction with the fibroblast growth factor FGF-2 was noticed for DP 4-12 depending on the degree of sulfation using the FGF-2-trypsin assay." @default.
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- W2000454017 date "2001-02-01" @default.
- W2000454017 modified "2023-10-18" @default.
- W2000454017 title "Sulfated β-(1→4)-galacto-oligosaccharides and their effect on angiogenesis" @default.
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- W2000454017 doi "https://doi.org/10.1016/s0008-6215(00)00305-0" @default.
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