FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000458321> ?p ?o ?g. }

• W2000458321 endingPage "233" @default.
• W2000458321 startingPage "223" @default.
• W2000458321 abstract "Multiheme cytochromes c are important in electron transfer pathways in reduction of both soluble and insoluble Fe(III) by Geobacter sulfurreducens. We determined the crystal structure at 3.2Å resolution of the first dodecaheme cytochrome c (GSU1996) along with its N-terminal and C-terminal hexaheme fragments at 2.6 and 2.15Å resolution, respectively. The macroscopic reduction potentials of the full-length protein and its fragments were measured. The sequence of GSU1996 can be divided into four c(7)-type domains (A, B, C and D) with homology to triheme cytochromes c(7). In cytochromes c(7) all three hemes are bis-His coordinated, whereas in c(7)-type domains the last heme is His-Met coordinated. The full-length GSU1996 has a 12nm long crescent shaped structure with the 12 hemes arranged along a polypeptide to form a nanowire of hemes; it has a modular structure. Surprisingly, while the C-terminal half of the protein consists of two separate c(7)-type domains (C and D) connected by a small linker, the N-terminal half of the protein has two c(7)-type domains (A and B) that form one structural unit. This is also observed in the AB fragment. There is an unexpected interaction between the hemes at the interface of domains A and B, which form a heme-pair with nearly parallel stacking of their porphyrin rings. The hemes adjacent to each other throughout the protein are within van der Waals distance which enables efficient electron exchange between them. For the first time, the structural details of c(7)-type domains from one multiheme protein were compared." @default.
• W2000458321 created "2016-06-24" @default.
• W2000458321 creator A5004649955 @default.
• W2000458321 creator A5019303330 @default.
• W2000458321 creator A5027902899 @default.
• W2000458321 creator A5037876190 @default.
• W2000458321 creator A5045503286 @default.
• W2000458321 creator A5054231979 @default.
• W2000458321 creator A5063972265 @default.
• W2000458321 creator A5065106096 @default.
• W2000458321 creator A5074718126 @default.
• W2000458321 creator A5081384131 @default.
• W2000458321 creator A5084749613 @default.
• W2000458321 date "2011-04-01" @default.
• W2000458321 modified "2023-09-27" @default.
• W2000458321 title "Structure of a novel dodecaheme cytochrome c from Geobacter sulfurreducens reveals an extended 12nm protein with interacting hemes" @default.
• W2000458321 cites W1576988856 @default.
• W2000458321 cites W1969538018 @default.
• W2000458321 cites W1969869893 @default.
• W2000458321 cites W1970977789 @default.
• W2000458321 cites W1976973589 @default.
• W2000458321 cites W1978965855 @default.
• W2000458321 cites W1991389128 @default.
• W2000458321 cites W1995017064 @default.
• W2000458321 cites W1995315243 @default.
• W2000458321 cites W1998607055 @default.
• W2000458321 cites W1999648041 @default.
• W2000458321 cites W2005630792 @default.
• W2000458321 cites W2010155510 @default.
• W2000458321 cites W2012172017 @default.
• W2000458321 cites W2014286639 @default.
• W2000458321 cites W2022963781 @default.
• W2000458321 cites W2032347469 @default.
• W2000458321 cites W2047705460 @default.
• W2000458321 cites W2050353266 @default.
• W2000458321 cites W2054525948 @default.
• W2000458321 cites W2065510140 @default.
• W2000458321 cites W2074618874 @default.
• W2000458321 cites W2080025885 @default.
• W2000458321 cites W2081197800 @default.
• W2000458321 cites W2082027006 @default.
• W2000458321 cites W2084971027 @default.
• W2000458321 cites W2088363148 @default.
• W2000458321 cites W2092345549 @default.
• W2000458321 cites W2108797154 @default.
• W2000458321 cites W2113878475 @default.
• W2000458321 cites W2117057402 @default.
• W2000458321 cites W2118215239 @default.
• W2000458321 cites W2131350133 @default.
• W2000458321 cites W2144081223 @default.
• W2000458321 cites W2149110469 @default.
• W2000458321 cites W2161693065 @default.
• W2000458321 cites W2167123041 @default.
• W2000458321 cites W2167654536 @default.
• W2000458321 doi "https://doi.org/10.1016/j.jsb.2010.11.022" @default.
• W2000458321 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21130881" @default.
• W2000458321 hasPublicationYear "2011" @default.
• W2000458321 type Work @default.
• W2000458321 sameAs 2000458321 @default.
• W2000458321 citedByCount "54" @default.
• W2000458321 countsByYear W20004583212012 @default.
• W2000458321 countsByYear W20004583212013 @default.
• W2000458321 countsByYear W20004583212014 @default.
• W2000458321 countsByYear W20004583212015 @default.
• W2000458321 countsByYear W20004583212016 @default.
• W2000458321 countsByYear W20004583212017 @default.
• W2000458321 countsByYear W20004583212018 @default.
• W2000458321 countsByYear W20004583212019 @default.
• W2000458321 countsByYear W20004583212020 @default.
• W2000458321 countsByYear W20004583212021 @default.
• W2000458321 countsByYear W20004583212022 @default.
• W2000458321 countsByYear W20004583212023 @default.
• W2000458321 crossrefType "journal-article" @default.
• W2000458321 hasAuthorship W2000458321A5004649955 @default.
• W2000458321 hasAuthorship W2000458321A5019303330 @default.
• W2000458321 hasAuthorship W2000458321A5027902899 @default.
• W2000458321 hasAuthorship W2000458321A5037876190 @default.
• W2000458321 hasAuthorship W2000458321A5045503286 @default.
• W2000458321 hasAuthorship W2000458321A5054231979 @default.
• W2000458321 hasAuthorship W2000458321A5063972265 @default.
• W2000458321 hasAuthorship W2000458321A5065106096 @default.
• W2000458321 hasAuthorship W2000458321A5074718126 @default.
• W2000458321 hasAuthorship W2000458321A5081384131 @default.
• W2000458321 hasAuthorship W2000458321A5084749613 @default.
• W2000458321 hasConcept C123669783 @default.
• W2000458321 hasConcept C178790620 @default.
• W2000458321 hasConcept C181199279 @default.
• W2000458321 hasConcept C185592680 @default.
• W2000458321 hasConcept C2776217839 @default.
• W2000458321 hasConcept C2779812452 @default.
• W2000458321 hasConcept C2780768313 @default.
• W2000458321 hasConcept C28859421 @default.
• W2000458321 hasConcept C29311851 @default.
• W2000458321 hasConcept C33347731 @default.
• W2000458321 hasConcept C523546767 @default.
• W2000458321 hasConcept C54355233 @default.
• W2000458321 hasConcept C55493867 @default.
• W2000458321 hasConcept C58123911 @default.

• next