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• W2000459196 abstract "The recognition that endothelin-1 contributes to the pathogenesis of pulmonary arterial hypertension has led to the development of clinically useful endothelin receptor antagonists that improve symptoms and functional capacity and alter the natural history of the disease in a beneficial way. The antagonists have varying degrees of selectivity for the two classes of endothelin receptor, termed ETA and ETB, and the varying degrees may translate into clinical differences. Endothelin receptor antagonists have become an integral part of therapy for pulmonary arterial hypertension, and the indications for their use are expanding." @default.
• W2000459196 created "2016-06-24" @default.
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• W2000459196 date "2007-03-01" @default.
• W2000459196 modified "2023-10-15" @default.
• W2000459196 title "Endothelin Receptor Antagonists in the Treatment of Pulmonary Arterial Hypertension" @default.
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• W2000459196 doi "https://doi.org/10.1016/j.ccm.2006.11.002" @default.
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