FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2000460129> ?p ?o ?g. }

• W2000460129 endingPage "391" @default.
• W2000460129 startingPage "380" @default.
• W2000460129 abstract "Abstract Reverse turns are a major class of protein secondary structure; they represent sites of chain reversal and thus sites where the globular character of a protein is created. It has been speculated for many years that turns may nucleate the formation of structure in protein folding, as their propensity to occur will favor the approximation of their flanking regions and their general tendency to be hydrophilic will favor their disposition at the solvent‐accessible surface. Reverse turns are local features, and it is therefore not surprising that their structural properties have been extensively studied using peptide models. In this article, we review research on peptide models of turns to test the hypothesis that the propensities of turns to form in short peptides will relate to the roles of corresponding sequences in protein folding. Turns with significant stability as isolated entities should actively promote the folding of a protein, and by contrast, turn sequences that merely allow the chain to adopt conformations required for chain reversal are predicted to be passive in the folding mechanism. We discuss results of protein engineering studies of the roles of turn residues in folding mechanisms. Factors that correlate with the importance of turns in folding indeed include their intrinsic stability, as well as their topological context and their participation in hydrophobic networks within the protein's structure. © 2008 Wiley Periodicals, Inc. Biopolymers 89: 380–391, 2008. This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com" @default.
• W2000460129 created "2016-06-24" @default.
• W2000460129 creator A5009621753 @default.
• W2000460129 creator A5081367513 @default.
• W2000460129 date "2008-02-14" @default.
• W2000460129 modified "2023-10-18" @default.
• W2000460129 title "Roles of β-turns in protein folding: From peptide models to protein engineering" @default.
• W2000460129 cites W1495099700 @default.
• W2000460129 cites W1505900198 @default.
• W2000460129 cites W1544623810 @default.
• W2000460129 cites W1563431405 @default.
• W2000460129 cites W1570122994 @default.
• W2000460129 cites W1586022877 @default.
• W2000460129 cites W1593625064 @default.
• W2000460129 cites W1593987163 @default.
• W2000460129 cites W1605897306 @default.
• W2000460129 cites W1754212277 @default.
• W2000460129 cites W1960408443 @default.
• W2000460129 cites W1963550288 @default.
• W2000460129 cites W1967263724 @default.
• W2000460129 cites W1968282981 @default.
• W2000460129 cites W1969349100 @default.
• W2000460129 cites W1972823428 @default.
• W2000460129 cites W1974138195 @default.
• W2000460129 cites W1974694176 @default.
• W2000460129 cites W1976044372 @default.
• W2000460129 cites W1976251900 @default.
• W2000460129 cites W1976650071 @default.
• W2000460129 cites W1976654525 @default.
• W2000460129 cites W1979195652 @default.
• W2000460129 cites W1981334795 @default.
• W2000460129 cites W1982529611 @default.
• W2000460129 cites W1983461039 @default.
• W2000460129 cites W1984816958 @default.
• W2000460129 cites W1989469518 @default.
• W2000460129 cites W1990320730 @default.
• W2000460129 cites W1992248599 @default.
• W2000460129 cites W1993534980 @default.
• W2000460129 cites W1993833825 @default.
• W2000460129 cites W1994625509 @default.
• W2000460129 cites W1995700633 @default.
• W2000460129 cites W1997066828 @default.
• W2000460129 cites W1998184675 @default.
• W2000460129 cites W1998488983 @default.
• W2000460129 cites W2003793115 @default.
• W2000460129 cites W2008708467 @default.
• W2000460129 cites W2009550389 @default.
• W2000460129 cites W2011236493 @default.
• W2000460129 cites W2015137784 @default.
• W2000460129 cites W2015195383 @default.
• W2000460129 cites W2016620531 @default.
• W2000460129 cites W2018645145 @default.
• W2000460129 cites W2020734433 @default.
• W2000460129 cites W2021889551 @default.
• W2000460129 cites W2023509200 @default.
• W2000460129 cites W2023633717 @default.
• W2000460129 cites W2026101733 @default.
• W2000460129 cites W2027688973 @default.
• W2000460129 cites W2028660378 @default.
• W2000460129 cites W2028893004 @default.
• W2000460129 cites W2029871341 @default.
• W2000460129 cites W2031439885 @default.
• W2000460129 cites W2034339598 @default.
• W2000460129 cites W2034647743 @default.
• W2000460129 cites W2034849137 @default.
• W2000460129 cites W2036389947 @default.
• W2000460129 cites W2036623301 @default.
• W2000460129 cites W2037964065 @default.
• W2000460129 cites W2038147123 @default.
• W2000460129 cites W2038226443 @default.
• W2000460129 cites W2040001997 @default.
• W2000460129 cites W2040299190 @default.
• W2000460129 cites W2040560905 @default.
• W2000460129 cites W2041459336 @default.
• W2000460129 cites W2043023293 @default.
• W2000460129 cites W2044268110 @default.
• W2000460129 cites W2045032792 @default.
• W2000460129 cites W2046769374 @default.
• W2000460129 cites W2047510784 @default.
• W2000460129 cites W2047620104 @default.
• W2000460129 cites W2052447197 @default.
• W2000460129 cites W2052677774 @default.
• W2000460129 cites W2053969512 @default.
• W2000460129 cites W2056561029 @default.
• W2000460129 cites W2058198562 @default.
• W2000460129 cites W2059158694 @default.
• W2000460129 cites W2059187210 @default.
• W2000460129 cites W2060081643 @default.
• W2000460129 cites W2060170099 @default.
• W2000460129 cites W2064589158 @default.
• W2000460129 cites W2066010782 @default.
• W2000460129 cites W2069663555 @default.
• W2000460129 cites W2069752955 @default.
• W2000460129 cites W2070265271 @default.
• W2000460129 cites W2072818573 @default.
• W2000460129 cites W2073032874 @default.
• W2000460129 cites W2074655761 @default.
• W2000460129 cites W2076121886 @default.

• next