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- W2000461302 abstract "We have fabricated miniature implantable fluorescence sensors for continuous fluorescence sensing applications in living subjects. These monolithically integrated GaAs-based sensors incorporate a 675 nm vertical-cavity surface-emitting laser (VCSEL), a GaAs PIN photodiode, and a fluorescence emission filter. We demonstrate high detection sensitivity for Cy5.5 far-red dye (50 nanoMolar) in living tissue, limited by the intrinsic background autofluorescence. These low cost, sensitive and scalable sensors are promising for long-term continuous monitoring of molecular dynamics for biomedical studies in freely moving animals." @default.
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- W2000461302 date "2010-05-27" @default.
- W2000461302 modified "2023-10-17" @default.
- W2000461302 title "Implantable semiconductor biosensor for continuous in vivo sensing of far-red fluorescent molecules" @default.
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- W2000461302 doi "https://doi.org/10.1364/oe.18.012513" @default.
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